The antineutrophil cytoplasmic antibodies (ANCA typical or not) in current medical practice

被引:4
|
作者
Renaudineau, Y. [3 ]
Beauvillard, D. [3 ]
Segalen, I. [2 ,3 ]
Leroyer, C. [1 ]
Le Meur, Y. [2 ]
Youinou, P. [1 ]
机构
[1] CHU Brest, Hop Cavale Blanche, Serv Pneumol, F-29609 Brest, France
[2] CHU Brest, Hop Cavale Blanche, Serv Nephrol, F-29609 Brest, France
[3] CHU Brest, Hop Morvan, Immunol Lab, F-29609 Brest, France
来源
IMMUNO-ANALYSE & BIOLOGIE SPECIALISEE | 2011年 / 26卷 / 01期
关键词
Antineutrophil cytoplasmic antibodies (ANCA); Vasculitis; Proteinase; 3; Myeloperoxidase (MPO); INTERNATIONAL CONSENSUS STATEMENT; WEGENERS-GRANULOMATOSIS; NECROTIZING GLOMERULONEPHRITIS; CRESCENTIC GLOMERULONEPHRITIS; SYSTEMIC VASCULITIS; DISEASE-ACTIVITY; AUTOANTIBODIES; PROTEINASE-3; NEUTROPHILS; MYELOPEROXIDASE;
D O I
10.1016/j.immbio.2010.12.002
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Antineutrophil cytoplasmic antibodies (ANCA) are important serological markers mostly for the small vessel systemic vasculitides. Numerous reports have established an interest for the combination of the indirect immunofluorescence (IFI) and the ELISA anti-PR3 and anti-MPO in such indication. However, conflicting results may exist between IFI and ELISA that require additional assays and such special measures are important to help and avoid clinical misinterpretation. (C) 2010 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:27 / 34
页数:8
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