Levels of heat shock protein transcripts in normal follicles and ovarian follicular cysts

被引:23
作者
Velazquez, Melisa M. L. [1 ,2 ]
Alfaro, Natalia S. [1 ,2 ]
Salvetti, Natalia R. [1 ,2 ]
Stangaferro, Matias L. [1 ]
Rey, Florencia [1 ,2 ]
Panzani, Carolina G. [1 ]
Ortega, Hugo H. [1 ,2 ]
机构
[1] Natl Univ Litoral FCV UNL, Fac Vet Sci, Dept Morphol Sci, RA-3080 Esperanza, Santa Fe, Argentina
[2] Argentine Natl Res Council CONICET, Buenos Aires, DF, Argentina
关键词
ovarian cyst; cow; cystic ovarian disease; anovulation; heat shock proteins; folliculogenesis; PROLIFERATION; APOPTOSIS; RECEPTORS; DISEASE; CELLS;
D O I
10.1016/S1642-431X(12)60072-2
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In the study, the gene expression of several heat shock proteins (HSPs) was determined in normal follicles and cystic follicles from cattle. A lower expression of HSP10 and HSP40 was observed in granulosa and theca cells of cysts compared to normal follicles. HSP27 was significantly less expressed in granulosa cells in cystic and large antral follicles than in other follicular categories. HSP60 and HSP90a expressions were highest in theca cells of cysts. However, HSP70 and HSP90b exhibited a lower expression in cysts than in healthy follicles. Reproductive Biology 2011 11 3: 276-283.
引用
收藏
页码:276 / 283
页数:8
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