Management of immune thrombocytopenia: 2022 update of Korean experts recommendations

被引：19

作者：

Park, Young Hoon ^{[1
]}

Kim, Dae-Young ^{[2
]}

Kim, Seongkoo ^{[3
]}

Choi, Young Bae ^{[4
]}

Shin, Dong-Yeop ^{[5
]}

Kim, Jin Seok ^{[6
]}

Lee, Won Sik ^{[7
]}

Mun, Yeung-Chul ^{[1
]}

Jang, Jun Ho ^{[8
]}

Lee, Jong Wook ^{[9
]}

Kook, Hoon ^{[10
]}

机构：

[1] Ewha Womans Univ, Mokdong Hosp, Dept Internal Med, Div Hematol Oncol, 1071 Anyangcheon Ro, Seoul 07985, South Korea

[2] Eulji Univ, Uijeongbu Eulji Med Ctr, Dept Internal Med, Daejeon, South Korea

[3] Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Dept Pediat, Seoul, South Korea

[4] Ajou Univ, Sch Med, Ajou Univ Hosp, Dept Pediat, Suwon, South Korea

[5] Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea

[6] Yonsei Univ, Coll Med, Severance Hosp, Dept Internal Med,Div Hematol, Seoul, South Korea

[7] Inje Univ, Busan Paik Hosp, Dept Internal Med, Busan, South Korea

[8] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Hematol Oncol, 81 Irwon Ro, Busan 06351, South Korea

[9] Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Hematol, Seoul, South Korea

[10] Chonnam Natl Univ, Hwasun Hosp, Dept Pediat, Hwasun, South Korea

来源：

BLOOD RESEARCH | 2022年 / 57卷 / 01期

关键词：

Immune thrombocytopenia; Recommendation; Management; HIGH-DOSE DEXAMETHASONE; QUALITY-OF-LIFE; LAPAROSCOPIC SPLENECTOMY; INTRAVENOUS IMMUNOGLOBULIN; RANDOMIZED-TRIAL; ADULT PATIENTS; MYCOPHENOLATE-MOFETIL; PURPURA ITP; ORAL CORTICOSTEROIDS; PREDNISONE THERAPY;

D O I：

10.5045/br.2022.2022043

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite the availability of therapies to treat patients with immune thrombocytopenia (ITP), there is currently little data from randomized trials to assist clinicians in managing patients. The evidence-based guidelines of the Korean Society of Hematology Aplastic Anemia Working Party (KSHAAWP) are intended to support patients and physicians in the management of ITP. Experts from the KSHAAWP discussed and described this guideline according to the current treatment situation for ITP in Korea and finalized the guidelines. The expert panel recommended the management of ITP in adult and pediatric patients with newly diagnosed, persistent, and chronic disease refractory to first-line therapy with minor bleeding. Management approaches include observation and administration of corticosteroids, intravenous immunoglobulin, anti-D immunoglobulin, and thrombopoietin receptor agonists. Currently, evidence supporting strong recommendations for various management approaches is lacking. Therefore, a large focus was placed on shared decision-making, especially regarding second-line treatment.

引用

页码：20 / 28

页数：9

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