Quantitative analysis of mitragynine, codeine, caffeine, chlorpheniramine and phenylephrine in a kratom (Mitragyna speciosa Korth.) cocktail using high-performance liquid chromatography

被引：39

作者：

Chittrakarn, Somsmorn ^{[1
]}

Penjamras, Pimpimol ^{[2
]}

Keawpradub, Niwat ^{[3
]}

机构：

[1] Prince Songkla Univ, Fac Sci, Dept Pharmacol, Hat Yai 90112, Songkhla, Thailand

[2] Prince Songkla Univ, Sci Equipment Ctr, Hat Yai 90112, Songkhla, Thailand

[3] Prince Songkla Univ, Fac Pharmaceut Sci, Dept Pharmacognosy & Pharmaceut Bot, Hat Yai 90112, Songkhla, Thailand

来源：

FORENSIC SCIENCE INTERNATIONAL | 2012年 / 217卷 / 1-3期

关键词：

Kratom cocktail; Mitragyna speciosa Korth; Mitragynine; HPLC; Codeine; Caffeine; Chlorpheniramine; ALKALOIDS; EXTRACT;

D O I：

10.1016/j.forsciint.2011.10.027

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A simple HPLC technique for determining mitragynine, codeine, caffeine, chlorpheniramine and phenylephrine in 'kratom cocktail' was developed. The analytical method for mitragynine, codeine and caffeine used an Eclipse XDB-C8 column. A Lichrospher CN column was using for analysing chlorpheniramine and phenylephrine. The correlation coefficient of each standard was between 0.9957 and 0.9993. The precision of the methods were between 0.700 and 7.108% RSD. The concentration of mitragynine, codeine, caffeine, chlorpheniramine and phenylephrine in 'kratom cocktail' was 90.021, 234.174, 73.986, 7.053 and 1.486 mg/L, respectively. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

引用

页码：81 / 86

页数：6

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