Multi-component synthesis and antimicrobial activity of novel imidazo[4,5-f] indol-7-yl)indolin-2-ones

被引：1

作者：

Reddy, Malladi Srinivas ^{[1
]}

Saini, Ramakrishna ^{[2
]}

Dontamalla, Sudheer Kumar ^{[3
]}

Suhasini, B. ^{[4
]}

机构：

[1] JNTU Hyderabad, Vaageswari Coll Pharm, Dept Pharmaceut Chem, Thimmapur, India

[2] Kakatiya Univ, Dept Chem, Warangal 506009, Andhra Pradesh, India

[3] KDR Govt Polytech, State Board Tech Educ & Training, Dept Pharm, Wanaparthy, India

[4] SVS Sch Pharm, Dept Pharmaceut Chem, Warangal, Andhra Pradesh, India

来源：

TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY | 2015年 / 97卷 / 07期

关键词：

imidazo[4,5-f]indol-7-yl)indolin-2-ones; ceric ammonium nitrate; multi-component reaction; antimicrobial activity; ALKALOIDS; DRUG;

D O I：

10.1080/02772248.2015.1060974

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

A three-component one-pot protocol has been investigated for the synthesis of imidazo[4,5-f]indol-7-yl)indolin-2-ones from the commercially available materials. Structures of these compounds were established on the basis of IR, H-1 NMR, and mass spectral data. The title compounds were evaluated for their antimicrobial activity. Two compounds exhibited the potent antimicrobial activity.

引用

页码：839 / 846

页数：8

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