Toward a Visible Light Mediated Photocyclization: Cu-Based Sensitizers for the Synthesis of [5]Helicene

被引：99

作者：

Hernandez-Perez, Augusto C. ^{[1
]}

Vlassova, Anna ^{[1
]}

Collins, Shawn K. ^{[1
]}

机构：

[1] Univ Montreal, Dept Chim, Ctr Green Chem & Catalysis, Montreal, PQ H3C 3J7, Canada

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 12期

关键词：

PHOTOREDOX CATALYSIS; COMPLEXES; PHOTOCHEMISTRY; PHOTOCATALYSIS; CYCLOADDITIONS; HELICENES; ALDEHYDES; ALCOHOLS;

D O I：

10.1021/ol300983b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A photochemical synthesis of [5]helicene employing a copper-based sensitizer 7 has been developed that avoids the disadvantages associated with the traditional UV light mediated method. The visible light mediated synthesis uses common glassware and a simple household light bulb without the competing formation of [2 + 2] cycloadducts, regioisomers, or the overoxidation product benzo[ghi]perylene 3. Preliminary results show that the reaction time can be significantly reduced through the use of a continuous flow strategy.

引用

页码：2988 / 2991

页数：4

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