A Case of Mixed Connective Tissue Disease Complicated by Pulmonary Hypertension and Ascites After Addition of Pulmonary Vasodilators

被引：0

作者：

Kusaka, Katsuhide ^{[1
]}

Nakano, Kazuhisa ^{[1
,2
]}

Fukuyo, Shunsuke ^{[1
]}

Miyazaki, Yusuke ^{[1
]}

Matsunaga, Satsuki ^{[1
]}

Tanaka, Yoshiya ^{[1
]}

机构：

[1] Univ Occupat & Environm Hlth, Sch Med, Dept Internal Med 1, Kitakyushu, Fukuoka, Japan

[2] Kawasaki Med Sch, Dept Rheumatol, Kawasaki, Kanagawa, Japan

来源：

MODERN RHEUMATOLOGY CASE REPORTS | 2022年 / 6卷 / 02期

关键词：

mixed connective tissue disease; pulmonary arterial hypertension; ascites; systemic lupus erythematosus; systemic sclerosis; ARTERIAL-HYPERTENSION; SYSTEMIC-SCLEROSIS;

D O I：

10.1093/mrcr/rxac019

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present the case of a 54-year-old woman with a long history of pulmonary hypertension (PH) associated with mixed connective tissue disease (MCTD). She was being treated with pulmonary vasodilators, including epoprostenol and bosetan, but her mean pulmonary arterial pressure (mPAP) gradually worsened. Although her mPAP began to improve with adding sildenafil, ascites occurred. Discontinuing newly initiated drugs and starting diuretics improved her ascites. This suggested that an intensification of the treatment with vasodilators might have led to ascites (on a background of a probable arteriovenous shunt formation) in this patient with a long history of PH.

引用

页码：203 / 208

页数：6

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