The effect of different solvent systems on physical properties of electrospun poly(glycerol sebacate)/poly(e-caprolactone) blend

被引:7
|
作者
Atari, Mehdi [1 ,2 ]
Mohammadalizadeh, Zahra [3 ]
Kharazi, Anoushe Zargar [2 ,3 ]
Javanmard, Shaghayegh Haghjooy [2 ]
机构
[1] Isfahan Univ Technol, Dept Mat Engn, Esfahan, Iran
[2] Isfahan Univ Med Sci, Appl Physiol Res Ctr, Isfahan Cardiovasc Res Inst, Esfahan, Iran
[3] Isfahan Univ Med Sci, Sch Adv Med Technol, Dept Biomat Nanotechnol & Tissue Engn, Esfahan, Iran
来源
POLYMER-PLASTICS TECHNOLOGY AND MATERIALS | 2022年 / 61卷 / 07期
关键词
Solvent; physical properties; electrospun scaffolds; MECHANICAL-PROPERTIES; NANOFIBROUS SCAFFOLDS; FIBER DIAMETER; MORPHOLOGY; SEBACATE); POLYCAPROLACTONE; CELLULOSE; CHITOSAN; GELATIN; DESIGN;
D O I
10.1080/25740881.2021.2022161
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Solvent type and solution viscosity are of great importance in affecting different traits of the electrospun scaffolds. This study aims to highlight the effect of different solvents on physicomechanical properties of PGS/PCL blend electrospun scaffolds. The PGS:PCL (2:1) blends were dissolved in five different solvent systems including DMF, DCM, DMSO, CF-AC, and CF-EtOH, with the final concentration of 18% w/v. Analyzing morphology indicated a more uniform fiber diameter and smaller pore size in PGS/PCL//CF-AC scaffolds. Also, the mechanical parameters were improved by the solvent upon using CF-AC more than DMF, correlated to better solution viscosity, spinnability and uniform fiber distribution.
引用
收藏
页码:789 / 802
页数:14
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