Determination of antioxidants and preservatives in cosmetics by SPME combined with GC-MS

被引：48

作者：

Tsai, Tzu-Feng ^{[1
,2
]}

Lee, Maw-Rong ^{[1
]}

机构：

[1] Natl Chung Hsing Univ, Dept Chem, Taichung 40227, Taiwan

[2] Providence Univ, Dept Cosmet Sci, Taichung 40332, Taiwan

来源：

CHROMATOGRAPHIA | 2008年 / 67卷 / 5-6期

关键词：

GC-MS; solid-phase microextraction; preservatives and antioxidants; cosmetics;

D O I：

10.1365/s10337-007-0514-1

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A rapid and simple procedure for the determination of antioxidants and preservatives in cosmetics has been developed utilizing solid-phase microextraction combined with GC-MS. A silica fiber coated with polyacrylate provided the highest extraction efficiency. Detection limits in the range from 0.4 to 8.5 ng mL(-1) were obtained. Linearity is over a wide range from 1 to 2,000 ng mL(-1) with a relative standard deviation under 16%. Cosmetic from a local supermarket were analysed for antioxidants and preservatives to demonstrate the effectiveness of the proposed method. The concentration of antioxidants and preservatives determined was 20-1,218 mu g g(-1) for methylparaben and 5-3,779 mu g g(-1) for propylparaben.

引用

页码：425 / 431

页数：7

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