Tracking research trends and hotspots in sperm DNA fragmentation testing for the evaluation of male infertility: a scientometric analysis

被引:32
作者
Baskaran, Saradha [1 ]
Agarwal, Ashok [1 ]
Panner Selvam, Manesh Kumar [1 ]
Finelli, Renata [1 ]
Robert, Kathy Amy [1 ]
Iovine, Concetta [1 ]
Pushparaj, Peter Natesan [2 ,3 ]
Samanta, Luna [1 ,4 ]
Harlev, Avi [5 ]
Henkel, Ralf [1 ,6 ]
机构
[1] Cleveland Clin, Amer Ctr Reprod Med, Mail Code X-11,10681 Carnegie Ave, Cleveland, OH 44195 USA
[2] King Abdulaziz Univ, Ctr Excellence Genom Med Res, Jeddah, Saudi Arabia
[3] King Abdulaziz Univ, Fac Appl Med Sci, Dept Med Lab Technol, Jeddah 21589, Saudi Arabia
[4] Ravenshaw Univ, Ctr Excellence Environm & Publ Hlth, Redox Biol Lab, Cuttack 753003, Odisha, India
[5] Ben Gurion Univ Negev, Soroka Univ Med Ctr, Dept Obstet & Gynecol, Beer Sheva, Israel
[6] Univ Western Cape, Dept Med Biosci, Bellville, South Africa
关键词
Scientometric analysis; Diagnosis; DNA fragmentation; Infertility; male; Prognosis; Publications; INFORMATION-SYSTEMS RESEARCH; PREGNANCY LOSS; CHROMATIN-STRUCTURE; OXIDATIVE STRESS; INCREASED RISK; MALE-FERTILITY; SEMEN QUALITY; TUNEL ASSAY; DAMAGE; ASSOCIATION;
D O I
10.1186/s12958-019-0550-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background This article describes the research trends in sperm DNA fragmentation (SDF) over the past 20 years (1999-2018) using a scientometric approach. Methods A stepwise approach was adopted to retrieve scientometric data (articles per year, authors, affiliations, journals, countries) from Scopus and analyze the publication pattern of SDF with reference to key areas of research in the field of Andrology. Results A total of 2121 articles were retrieved related to SDF. Our data revealed an increasing research trend in SDF (n = 33 to n = 173) over the past 20 years (R-2 = 0.894). Most productive country in publications was the USA (n = 450), while Agarwal A. (n = 129) being the most productive author. Most of the articles in SDF were primarily focused on lifestyle (n = 157), asthenozoospermia (n = 135) and varicocele (130). Mechanistic studies on SDF were published twice as much as prognostic/diagnostic studies, with significant emphasis on oxidative stress. Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) was the most widely used technique to evaluate SDF. Publications on SDF related to assisted reproductive techniques also showed a linear increasing trend (R-2 = 0.933). Conclusions Our analysis revealed an increasing trend in SDF publications predominantly investigating lifestyle, asthenozoospermia and varicocele conditions with TUNEL being the most widely used technique. A substantial increase in research is warranted to establish SDF as prognostic/diagnostic parameter to evaluate clinical scenarios and ART outcomes.
引用
收藏
页数:13
相关论文
共 75 条
[51]   The study of spermatic DNA fragmentation and sperm motility in infertile subjects [J].
Peluso, Giuseppina ;
Palmieri, Alessandro ;
Cozza, Pietro Paolo ;
Morrone, Giancarlo ;
Verze, Paolo ;
Longo, Nicola ;
Mirone, Vincenzo .
ARCHIVIO ITALIANO DI UROLOGIA E ANDROLOGIA, 2013, 85 (01) :8-13
[52]   Comprehensive analysis of sperm DNA fragmentation by five different assays: TUNEL assay, SCSA, SCD test and alkaline and neutral Comet assay [J].
Ribas-Maynou, J. ;
Garcia-Peiro, A. ;
Fernandez-Encinas, A. ;
Abad, C. ;
Amengual, M. J. ;
Prada, E. ;
Navarro, J. ;
Benet, J. .
ANDROLOGY, 2013, 1 (05) :715-722
[53]   Coffee and caffeine intake and male infertility: a systematic review [J].
Ricci, Elena ;
Vigano, Paola ;
Cipriani, Sonia ;
Somigliana, Edgardo ;
Chiaffarino, Francesca ;
Bulfoni, Alessandro ;
Parazzini, Fabio .
NUTRITION JOURNAL, 2017, 16
[54]   A bibliometric study of scientific literature in Scopus on botanicals for treatment of androgenetic alopecia [J].
Rondanelli, Mariangela ;
Perna, Simone ;
Peroni, Gabriella ;
Guido, Davide .
JOURNAL OF COSMETIC DERMATOLOGY, 2016, 15 (02) :120-130
[55]   Sperm DNA fragmentation index as a promising predictive tool for male infertility diagnosis and treatment management - meta-analyses [J].
Santi, Daniele ;
Spaggiari, Giorgia ;
Simoni, Manuela .
REPRODUCTIVE BIOMEDICINE ONLINE, 2018, 37 (03) :315-326
[56]   A systematic review on sperm DNA fragmentation in male factor infertility: Laboratory assessment [J].
Selvam, Manesh Kumar Panner ;
Agarwal, Ashok .
ARAB JOURNAL OF UROLOGY, 2018, 16 (01) :65-76
[57]   Age of tobacco use initiation and association with current use and nicotine dependence among US middle and high school students, 2014-2016 [J].
Sharapova, Saida ;
Reyes-Guzman, Carolyn ;
Singh, Tushar ;
Phillips, Elyse ;
Marynak, Kristy L. ;
Agaku, Israel .
TOBACCO CONTROL, 2020, 29 (01) :49-54
[58]  
Sharlip ID, 2002, FERTIL STERIL, V77, P873, DOI 10.1016/S0015-0282(02)03105-9
[59]   Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay using bench top flow cytometer for evaluation of sperm DNA fragmentation in fertility laboratories: protocol, reference values, and quality control [J].
Sharma, Rakesh ;
Ahmad, Gulfam ;
Esteves, Sandro C. ;
Agarwal, Ashok .
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2016, 33 (02) :291-300
[60]   Role of reactive oxygen species in male infertility [J].
Sharma, RK ;
Agarwal, A .
UROLOGY, 1996, 48 (06) :835-850