Paroxysmal Nocturnal Hemoglobinuria -- Hemolysis before and after Eculizumab.

被引：53
作者：
Risitano, Antonio M. [1 ]
Notaro, Rosario [2 ]
Luzzatto, Lucio [2 ]
Hill, Anita [3 ]
Kelly, Richard [3 ]
Hillmen, Peter [3 ]
机构：
[1] Univ Naples Federico 2, Naples, Italy
[2] Ist Toscano Tumori, Florence, Italy
[3] St James Univ Hosp, Leeds, W Yorkshire, England
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2010年 / 363卷 / 23期
关键词：
D O I：
10.1056/NEJMc1010351
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2270 / 2273
页数：3
相关论文
共 5 条
[1]   Hemolytic Anemia after Eculizumab in Paroxysmal Nocturnal Hemoglobinuria [J].
Berzuini, Alessandra ;
Montanelli, Fabio ;
Prati, Daniele .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (10) :993-994
[2]   Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization [J].
Hill, Anita ;
Rother, Russell P. ;
Arnold, Louise ;
Kelly, Richard ;
Cullen, Matthew J. ;
Richards, Stephen J. ;
Hillmen, Peter .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (04) :567-573
[3]   Diagnosis and management of paroxysmal nocturnal hemoglobinuria [J].
Parker, C ;
Omine, M ;
Richards, S ;
Nishimura, J ;
Bessler, M ;
Ware, R ;
Hillmen, P ;
Luzzatto, L ;
Young, N ;
Kinoshita, T ;
Rosse, W ;
Socié, G .
BLOOD, 2005, 106 (12) :3699-3709
[4]   Hemoglobin normalization after spienectomy in a paroxysmal nocturnal hemoglobinuria patient treated by eculizumab [J].
Risitano, Antonio M. ;
Marando, Ludovica ;
Seneca, Elisa ;
Rotoli, Bruno .
BLOOD, 2008, 112 (02) :449-451
[5]   Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab [J].
Risitano, Antonio M. ;
Notaro, Rosario ;
Marando, Ludovica ;
Serio, Bianca ;
Ranaldi, Danilo ;
Seneca, Elisa ;
Ricci, Patrizia ;
Alfinito, Fiorella ;
Camera, Andrea ;
Gianfaldoni, Giacomo ;
Amendola, Angela ;
Boschetti, Carla ;
Di Bona, Eros ;
Fratellanza, Giorgio ;
Barbano, Filippo ;
Rodeghiero, Francesco ;
Zanella, Alberto ;
Iori, Anna Paola ;
Selleri, Carmine ;
Luzzatto, Lucio ;
Rotoli, Bruno .
BLOOD, 2009, 113 (17) :4094-4100
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