Lipoxygenase-inhibiting lignans from Clematis mandshurica

被引:7
作者
Fu, Qiang [1 ]
Zhou, Chuang [1 ]
Ma, Yu [1 ]
Yang, Min [1 ]
Yuan, Hai-Mei [1 ]
Chen, Jiang [1 ]
Liu, Pei-Xi [2 ]
机构
[1] Chengdu Univ, Sch Pharm & Bioengn, Chengdu 610106, Sichuan, Peoples R China
[2] Sichuan Prov Peoples Hosp, Dept Gastroenterol & Hepatol, Chengdu 610072, Sichuan, Peoples R China
关键词
Ranunculaceae; Clematis mandshurica; lignan; lipoxygenase-inhibiting activiy; TRITERPENE SAPONINS; MANSHURICA;
D O I
10.1080/10286020.2016.1251419
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The EtOH extract of the roots and rhizomes of Clematis mandshurica afforded two new lignans clemomanshurinane C (1) and clemomanshurinane D (2), and three known compounds (3-5). Their structures were elucidated on the basis of spectroscopic means and hydrolysis products. All compounds displayed moderate inhibitory activity against enzyme lipoxygenase. [GRAPHICS] .
引用
收藏
页码:884 / 889
页数:6
相关论文
共 10 条
[1]   NEW LIGNAN GLUCOSIDES FROM STEMMADENIA-MINIMA [J].
ACHENBACH, H ;
LOWEL, M ;
WAIBEL, R ;
GUPTA, M ;
SOLIS, P .
PLANTA MEDICA, 1992, 58 (03) :270-272
[2]   The genus Clematis (Ranunculaceae): Chemical and pharmacological perspectives [J].
Chawla, Rakesh ;
Kumar, Suresh ;
Sharma, Anupam .
JOURNAL OF ETHNOPHARMACOLOGY, 2012, 143 (01) :116-150
[3]   Lignans from Strophanthus gratus [J].
Cowan, S ;
Stewart, M ;
Abbiw, DK ;
Latif, Z ;
Sarker, SD ;
Nash, RJ .
FITOTERAPIA, 2001, 72 (01) :80-82
[4]   Triterpene Saponins from Clematis chinensis and Their Potential Anti-inflammatory Activity [J].
Fu, Qiang ;
Zan, Ke ;
Zhao, Mingbo ;
Zhou, Sixiang ;
Shi, Shepo ;
Jiang, Yong ;
Tu, Pengfei .
JOURNAL OF NATURAL PRODUCTS, 2010, 73 (07) :1234-1239
[5]  
Kizu H, 1995, CHEM PHARM BULL, V43, P2187
[6]   Lignans from the roots and rhizomes of Clematis manshurica [J].
Shi, She-Po ;
Jiang, Dan ;
Dong, Cai-Xia ;
Tu, Peng-Fei .
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2006, 61 (10) :1299-1303
[7]   Alkaloids from Clematis manshurica Rupr. [J].
Shi, She-Po ;
Tu, Peng-Fei ;
Dong, Cai-Xia ;
Jiang, Dan .
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2006, 8 (1-2) :73-78
[8]   Triterpene Saponins from Clematis mandshurica [J].
Shi, Shepo ;
Jiang, Dan ;
Dong, Caixia ;
Tu, Pengfei .
JOURNAL OF NATURAL PRODUCTS, 2006, 69 (11) :1591-1595
[9]   LIPOXIDASE [J].
TAPPEL, AL .
METHODS IN ENZYMOLOGY, 1962, 5 :539-541
[10]   Phenylpropanoid and lignan glycosides from the aerial parts of Lespedeza cuneata [J].
Zhou, Jian ;
Li, Chuang-Jun ;
Yang, Jing-Zhi ;
Ma, Jie ;
Wu, Lian-Qiu ;
Wang, Wen-Jie ;
Zhang, Dong-Ming .
PHYTOCHEMISTRY, 2016, 121 :58-64