Answers and questions from the KvAP structures

被引：65

作者：

Cohen, BE

Grabe, M

Jan, LY ^{[1
]}

机构：

[1] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Dept Biochem, San Francisco, CA 94143 USA

来源：

NEURON | 2003年 / 39卷 / 03期

关键词：

D O I：

10.1016/S0896-6273(03)00472-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The recent landmark structures of KvAP, a voltage-gated potassium (Kv) channel, provide the first high-resolution experimental structural models of this class of proteins. Previous extensive studies of Kv channels provide a means to evaluate and interpret the KvAP structures. In this minireview, we survey different experimental approaches to Kv channels and map these findings to KvAP, showing that the relationship between the KvAP structures and other Kv channels is uncertain.

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页码：395 / 400

页数：6

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