A simple approach to covalent functionalization of boron nitride nanotubes

被引：173

作者：

Ciofani, Gianni ^{[1
]}

Genchi, Giada Graziana ^{[2
]}

Liakos, Ioannis ^{[3
]}

Athanassiou, Athanassia ^{[3
]}

Dinucci, Dinuccio ^{[4
]}

Chiellini, Federica ^{[4
]}

Mattoli, Virgilio

机构：

[1] Scuola Super Sant Anna, Italian Inst Technol, Smart Mat Lab, Ctr MicroBioRobot, I-56025 Pisa, Italy

[2] Scuola Super Sant Anna, BioRobot Inst, I-56025 Pisa, Italy

[3] Italian Inst Technol, Ctr Biomol Nanotechnol, I-73010 Lecce, Italy

[4] Univ Pisa, Lab Bioact Polymer Mat Biomed & Environm Applicat, I-56010 Pisa, Italy

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2012年 / 374卷

关键词：

Boron nitride nanotubes; APTES; Covalent modification; Nanomedicine; WALLED CARBON NANOTUBES; BN NANOTUBES; CELLS; 3-AMINOPROPYLTRIETHOXYSILANE; CYTOCOMPATIBILITY; PROTEINS; SYSTEMS; ASSAY; PURE;

D O I：

10.1016/j.jcis.2012.01.049

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A novel and simple method for the preparation of chemically functionalized boron nitride nanotubes (BNNTs) is presented. Thanks to a strong oxidation followed by the silanization of the surface through 3-aminopropyl-triethoxysilane (APTES), BNNTs exposing amino groups on their surface were successfully obtained. The efficacy of the procedure was assessed with EDS and XPS analyses, which demonstrated a successful functionalization of similar to 15% boron sites. This approach opens interesting perspectives for further modification of BNNTs with several kinds of molecules. Since, in particular, biomedical applications are envisaged, we also demonstrated in vitro biocompatibility and cellular up-take of the functionalized BNNTs. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：308 / 314

页数：7

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