Local Antibiotic Delivery Systems in Diabetic Foot Osteomyelitis: Time for One Step Beyond?

被引：27

作者：

Panagopoulos, Periklis ^{[1
]}

Drosos, Georgios ^{[2
]}

Maltezos, Efstratios ^{[1
,3
]}

Papanas, Nikolaos ^{[3
]}

机构：

[1] Democritus Univ Thrace, Dept Internal Med 2, Unit Infect Dis, Alexandroupolis 68100, Greece

[2] Democritus Univ Thrace, Orthopaed Dept, Alexandroupolis 68100, Greece

[3] Democritus Univ Thrace, Dept Internal Med 2, Outpatient Clin Diabet Foot, Alexandroupolis 68100, Greece

来源：

INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS | 2015年 / 14卷 / 01期

关键词：

antibiotics; delivery systems; diabetes mellitus; diabetic foot; infections; osteomyelitis; treatment; CRYSTALLIC SEMIHYDRATE FORM; CALCIUM-SULFATE PELLETS; IN-VITRO ELUTION; NONSURGICAL MANAGEMENT; INFECTIONS; DIAGNOSIS; SWAB;

D O I：

10.1177/1534734614566937

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In patients with diabetes mellitus, osteomyelitis is a severe, difficult-to-treat form of foot infection. In the management of diabetic foot osteomyelitis, carriers for local delivery of antimicrobial agents have begun to be tried, in an attempt to provide high local antibiotic concentrations. Randomized clinical trials are now expected to clarify when this new approach should be used and how it can be integrated into the overall therapeutic strategy for diabetic foot osteomyelitis.

引用

页码：87 / 91

页数：5

共 41 条

[1]

[Anonymous], 2001, PRACTICAL DIABETES

[2] Gram-Negative Diabetic Foot Osteomyelitis: Risk Factors and Clinical Presentation [J].