Regioselective syntheses of fully-substituted 1,2,3-triazoles: the CuAAC/C-H bond functionalization nexus

被引：221

作者：

Ackermann, Lutz ^{[1
]}

Potukuchi, Harish Kumar ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2010年 / 8卷 / 20期

关键词：

PALLADIUM-CATALYZED ARYLATION; AZIDE-ALKYNE CYCLOADDITION; MEDIATED DIRECT ARYLATION; CROSS-COUPLING REACTIONS; C-H; CARBON-HYDROGEN; CLICK CHEMISTRY; ARYL CHLORIDES; 1,3-DIPOLAR CYCLOADDITIONS; DIRECT ALKYNYLATION;

D O I：

10.1039/c0ob00212g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Regioselective syntheses of 1,4,5-trisubstituted 1,2,3- triazoles were accomplished by three different strategies, relying on (i) the interception of stoichiometrically formed 5-cuprated-1,2,3-triazoles, (ii) the use of stoichiometrically functionalized alkynes or (iii) catalytic C-H bond functionalizations. This perspective article summarizes progress in this research area until June 2010.

引用

页码：4503 / 4513

页数：11

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