Human Monkeypox: A Comprehensive Narrative Review and Analysis of the Public Health Implications

被引:46
作者
Di Gennaro, Francesco [1 ]
Veronese, Nicola [2 ]
Marotta, Claudia [3 ]
Shin, Jae Il [4 ]
Koyanagi, Ai [5 ,6 ]
Silenzi, Andrea [3 ]
Antunes, Mario [7 ]
Saracino, Annalisa [1 ]
Bavaro, Davide Fiore [1 ]
Soysal, Pinar [8 ]
Segala, Francesco Vladimiro [1 ]
Butler, Laurie [9 ]
Milano, Eugenio [1 ]
Barbagallo, Mario [2 ]
Barnett, Yvonne [9 ]
Parris, Christopher [9 ]
Nicastri, Emanuele [10 ]
Pizzol, Damiano [11 ]
Smith, Lee [12 ]
机构
[1] Univ Bari, Univ Hosp Policlin, Clin Infect Dis, I-70121 Bari, Italy
[2] Univ Palermo, Dept Internal Med & Geriatr, Geriatr Unit, I-90133 Palermo, Italy
[3] Minist Hlth, Gen Directorate Hlth Prevent, I-00144 Rome, Italy
[4] Yonsei Univ, Dept Pediat, Coll Med, Seoul 03722, South Korea
[5] ISCIII, Res & Dev Unit, Parc Sanitari St Joan de Deu, CIBERSAM, Barcelona 08010, Spain
[6] ICREA, Passeig Lluis Co 23, Barcelona 08010, Spain
[7] Catholic Univ Mozambique, Dept Surg, Beira 13016, Mozambique
[8] Bezmialem Vakif Univ, Fac Med, Dept Geriatr Med, TR-34093 Istanbul, Turkey
[9] Anglia Ruskin Univ, Fac Sci & Engn, Cambridge CB1 1PT, England
[10] IRCCS, Natl Inst Infect Dis, Lazzaro Spallanzani, Via Portuense 292, I-00149 Rome, Italy
[11] Italian Agcy Dev Cooperat, Khartoum 00135, Sudan
[12] Anglia Ruskin Univ, Ctr Hlth Performance & Wellbeing, Cambridge CB1 1PT, England
关键词
monkeypox (MPX); epidemiology; zoonotic pandemic; smallpox; TO-HUMAN TRANSMISSION;
D O I
10.3390/microorganisms10081633
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Recently, numerous cases of monkeypox were reported from several non-endemic countries in Europe, North America, and Oceania, suggesting an unusual and alarming public health issue, particularly considering that the disease is not directly related to human or animal travels. Attention is currently being drawn to this phenomenon since more than 70% of the global population is no longer vaccinated against smallpox. Indeed, the smallpox vaccination also confers some indirect degree of protection against other poxviruses, including monkeypox. We performed a narrative review to describe the existing literature with regard to monkeypox using the MEDLINE, EMBASE, and Scopus databases. This review aims to provide updated evidence of findings on the epidemiology, clinical features, diagnosis, management, and prevention of monkeypox, also considering the concurrent zoonotic pandemic caused by the COVID-19 coronavirus, SARS-CoV-2.
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页数:10
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