A common and stereoselective strategy for the synthesis of N,O,O,O-tetra-acetyl D-ribo-(2S,3S,4R)-phytosphingosine and 2-epi-jaspine B

被引：29

作者：

Rao, G. Srinivas ^{[1
]}

Rao, B. Venkateswara ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Div 3, Hyderabad 500607, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 38期

关键词：

PACHASTRISSAMINE JASPINE-B; D-RIBO-PHYTOSPHINGOSINE; D-LYXO-PHYTOSPHINGOSINE; ASYMMETRIC-SYNTHESIS; CYTOTOXIC ANHYDROPHYTOSPHINGOSINE; MARINE SPONGE; BIOLOGICAL SIGNIFICANCE; EFFICIENT SYNTHESIS; CONJUGATE ADDITION; D-XYLOSE;

D O I：

10.1016/j.tetlet.2011.07.032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A common and stereoselective strategy for the synthesis of N,O,O,O-tetra-acetyl D-ribo-(2S,3S,4R)-phytosphingosine and 2-epi-jaspine B was achieved by using Grignard addition on N-benzyl sugar lactamine and Wittig olefination as key steps. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：4861 / 4864

页数：4

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