A common and stereoselective strategy for the synthesis of N,O,O,O-tetra-acetyl D-ribo-(2S,3S,4R)-phytosphingosine and 2-epi-jaspine B

被引：29
作者：
Rao, G. Srinivas [1 ]
Rao, B. Venkateswara [1 ]
机构：
[1] Indian Inst Chem Technol, Organ Div 3, Hyderabad 500607, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 2011年 / 52卷 / 38期
关键词：
PACHASTRISSAMINE JASPINE-B; D-RIBO-PHYTOSPHINGOSINE; D-LYXO-PHYTOSPHINGOSINE; ASYMMETRIC-SYNTHESIS; CYTOTOXIC ANHYDROPHYTOSPHINGOSINE; MARINE SPONGE; BIOLOGICAL SIGNIFICANCE; EFFICIENT SYNTHESIS; CONJUGATE ADDITION; D-XYLOSE;
D O I：
10.1016/j.tetlet.2011.07.032
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A common and stereoselective strategy for the synthesis of N,O,O,O-tetra-acetyl D-ribo-(2S,3S,4R)-phytosphingosine and 2-epi-jaspine B was achieved by using Grignard addition on N-benzyl sugar lactamine and Wittig olefination as key steps. (C) 2011 Elsevier Ltd. All rights reserved.
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收藏
页码：4861 / 4864
页数：4
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