Diarylcyclohexanones: synthons for new bicyclic compounds

被引：1

作者：

Ahmad, Sarfraz ^{[1
]}

Weis, Robert ^{[1
]}

Faist, Johanna ^{[1
]}

Wolkinger, Volker ^{[1
]}

Saf, Robert ^{[2
]}

Belaj, Ferdinand ^{[3
]}

Brun, Reto ^{[4
]}

Kaiser, Marcel ^{[4
]}

Seebacher, Werner ^{[1
]}

机构：

[1] Graz Univ, Inst Pharmaceut Sci, Graz, Austria

[2] Graz Univ Technol, ICTM, A-8010 Graz, Austria

[3] Graz Univ, Inst Chem, Graz, Austria

[4] Swiss Trop & Publ Hlth Inst, Basel, Switzerland

来源：

MONATSHEFTE FUR CHEMIE | 2012年 / 143卷 / 01期

关键词：

Cyclizations; Crystal structure; Drug research; Michael addition; Antiprotozoals; TRYPANOSOMA-BRUCEI-RHODESIENSE; ALPHA; BETA-UNSATURATED KETONES; GAMBIENSE; NONANES;

D O I：

10.1007/s00706-011-0679-z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We used 4-acetyl-3,5-diarylcyclohexanones bearing two different aromatic rings as synthons for the preparation of 6,7-diaryl-4-(dialkylamino)bicyclo[2.2.2]octanones, starting materials for new antiprotozoals.

引用

页码：145 / 152

页数：8

共 50 条

[21] Cyclometallated gold(III) hydroxides as versatile synthons for Au-N, Au-C complexes and luminescent compounds
Rosca, Dragos-Adrian
Smith, Dan A.
Bochmann, Manfred
CHEMICAL COMMUNICATIONS, 2012, 48 (58) : 7247 - 7249
[22] Efficient synthesis of α-(fluoro/chloro/methoxy)disulfonylmethane derivatives as tunable substituted methyl synthons via a new C-S bond forming strategy
Prakash, G. K. Surya
Wang, Fang
Ni, Chuanfa
Thomas, Tito Joe
Olah, George A.
JOURNAL OF FLUORINE CHEMISTRY, 2010, 131 (10) : 1007 - 1012
[23] In Silico Design and In Vitro Assessment of Bicyclic Trifluoromethylated Pyrroles as New Antibacterial and Antifungal Agents
Hodyna, Diana
Klipkov, Anton
Kachaeva, Maryna
Shulha, Yurii
Gerus, Igor
Metelytsia, Larysa
Kovalishyn, Vasyl
CHEMISTRY & BIODIVERSITY, 2024, 21 (08)
[24] Development of a new bicyclic imidazole nucleophilic organocatalyst for direct enantioselective C-acylation
Zhou, Muxing
He, Ende
Zhang, Lu
Chen, Jianzhong
Zhang, Zhenfeng
Liu, Yangang
Zhang, Wanbin
ORGANIC CHEMISTRY FRONTIERS, 2019, 6 (24) : 3969 - 3972
[25] An approach to new chiral bicyclic imines and amines via Horner-Wadsworth-Emmons reaction
Iwanejko, Jakub
Sowinski, Mateusz
Wojaczynska, Elzbieta
Olszewski, Tomasz K.
Gorecki, Marcin
RSC ADVANCES, 2020, 10 (25) : 14618 - 14629
[26] New Bicyclic Amines: Synthesis and SARs of their Action Against the Causative Organisms of Malaria and Sleeping Sickness
Weis, R.
Seebacher, W.
CURRENT MEDICINAL CHEMISTRY, 2009, 16 (11) : 1426 - 1441
[27] Crystal Structure of New Heusler Compounds
Graf, Tania
Casper, Frederick
Winterlik, Juergen
Balke, Benjamin
Fecher, Gerhard H.
Felser, Claudia
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2009, 635 (6-7): : 976 - 981
[28] Ru(II) and Ru(III) complexes containing N-acylthiourea ligands: Supramolecular structures and synthons, reduction, and reaction pathway of aromatic nitro compounds
Uysal, Muhammet Ebubekir
Solmaz, Ummuhan
Arslan, Hakan
APPLIED ORGANOMETALLIC CHEMISTRY, 2023, 37 (07)
[29] Synthesis of carboxylactones and new heterocyclic compounds
Kochikyan, TV
Samvelyan, MA
Haroutyunyan, VS
Avetissyan, AA
SYNTHETIC COMMUNICATIONS, 2006, 36 (11) : 1613 - 1620
[30] Catalytic Reductive Amination of Aldehydes and Ketones With Nitro Compounds: New Light on an Old Reaction
Sukhorukov, Alexey Yu.
FRONTIERS IN CHEMISTRY, 2020, 8

← 1 2 3 4 5 →