Solution phase synthesis of (1->5)-amide linked sugar amino acid dimers derived from sialic acids

被引：41

作者：

Gervay, J

Flaherty, TM

Nguyen, C

机构：

[1] Department of Chemistry, University of Arizona, Tucson

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 09期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(97)00138-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Carboxy-protected amino derivatives and amino-protected carboxy derivatives of three different C-2 analogs as well as a 2,3-dehydro NeuAc were prepared. These monomers were coupled in solution using BOP activation of the carboxy terminus to form (1-->5)-amide linked dimers of sialyl amino acid derivatives. (C) 1997 Elsevier Science Ltd.

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页码：1493 / 1496

页数：4

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