Germline TP53 c.566C>T mutation incidentally diagnosed during treatment for acute myeloid leukemia: A case report

被引：1
作者：
Sato, Hiroshi [1 ]
Matsuo, Seiki [1 ]
Ando, Yukiko [1 ]
Imamura, Yuko [1 ]
Hirose, Masaya [1 ]
机构：
[1] Hyogo Prefectural Amagasaki Gen Med Ctr, Dept Clin Genet, Amagasaki, Hyogo, Japan
来源：
CLINICAL CASE REPORTS | 2021年 / 9卷 / 12期
关键词：
acute myeloid leukemia; genetic counseling; TP53; variant of uncertain significance;
D O I：
10.1002/ccr3.5221
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
TP53 mutations in acute myeloid leukemia (AML) are associated with poor outcomes. The number of somatic and/or germline genetic tests for therapy is increasing. Patients with such incidental findings should undergo adequate genetic counseling.
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页数：5
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