Nocturnal Enuresis in Sickle Cell: Sociodemographic, Medical, and Quality of Life Factors

被引:1
作者
Porter, Jerlym S. [1 ]
Paladino, Andrew J. [1 ,2 ]
Russell, Kathryn [1 ]
Rupff, Rebecca [1 ,3 ]
Griffith, Jamilla [1 ]
Mai, Yujiao [4 ]
Zhang, Hui [4 ,5 ]
Hankins, Jane S. [6 ]
Wang, Winfred C. [6 ]
机构
[1] St Jude Childrens Res Hosp, Dept Psychol, 262 Danny Thomas Pl,Mail Stop 740, Memphis, TN 38105 USA
[2] Univ Tennessee, Ctr Hlth Sci, Coll Med, Dept Prevent Med, Memphis, TN 38163 USA
[3] Alabama Coll Osteopath Med, Dothan, AL USA
[4] St Jude Childrens Res Hosp, Dept Biostat, 332 N Lauderdale St, Memphis, TN 38105 USA
[5] Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, Chicago, IL 60611 USA
[6] St Jude Childrens Res Hosp, Dept Hematol, 332 N Lauderdale St, Memphis, TN 38105 USA
关键词
enuresis; hematology; quality of life; sickle cell disease; GENERIC CORE SCALES; YOUNG-ADULTS; CLINICAL-TRIAL; CHILDREN; DISEASE; SLEEP; RELIABILITY; FEASIBILITY; ADOLESCENTS; VALIDITY;
D O I
10.1093/jpepsy/jsab079
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Objective Nocturnal enuresis is more prevalent in youth with sickle cell disease (SCD) compared to the general population. The purpose of this study is to estimate prevalence of nocturnal enuresis using diagnostic criteria and identify associated sociodemographic, medical, and health-related quality of life (HRQOL) factors. Methods Youth with SCD (N = 248; ages 6.00-17.99 years) and their caregivers completed semi-structured interviews and questionnaires. HRQOL was measured using the Pediatric Quality of Life (PedsQL) Inventory. Medical information was abstracted from medical record. We generated multivariable logistic regression models to examine associations between factors and current nocturnal enuresis and nocturnal enuresis occurring any time in the past (lifetime). Results Among participants (mean age, 11.3 +/- 3.6 years; 50.8% male), 21.4% reported current nocturnal enuresis and 46% reported lifetime nocturnal enuresis. Male sex [odds ratio (OR), 2.57; p = .001], difficulty arousing from sleep (OR, 3.57; p < .001), higher school functioning HRQOL (OR, 1.02; p = .014), and higher fetal hemoglobin levels (OR, 1.03; p = .048) were associated with lifetime nocturnal enuresis. Younger age (OR, 1.16; p = .005), higher youth-reported fatigue (OR, 1.01; p = .045), difficulty arousing from sleep (OR, 4.92; p < .001), and higher lactate dehydrogenase levels (OR, 1.00; p = .042) were associated with current nocturnal enuresis. Conclusions Nocturnal enuresis is prevalent in youth with SCD and is associated with HRQOL, diminished sleep, greater fatigue, and disease severity markers. Routine assessment of sleep behaviors and fatigue are necessary when treating patients with SCD to understand the impact of nocturnal enuresis on HRQOL.
引用
收藏
页码:75 / 85
页数:11
相关论文
共 57 条
[1]  
Ahmadi Mehrnaz, 2018, Int J Hematol Oncol Stem Cell Res, V12, P69
[2]  
Ahmed FE., 2017, MED SURG UROLOGY, V6, P191, DOI DOI 10.4172/2168-9857.1000191
[3]   Effect of hydroxyurea treatment on renal function parameters: Results from the multi-center placebo-controlled BABY HUG clinical trial for infants with sickle cell anemia [J].
Alvarez, Ofelia ;
Miller, Scott T. ;
Wang, Winfred C. ;
Luo, Zhaoyu ;
McCarville, M. Beth ;
Schwartz, George J. ;
Thompson, Bruce ;
Howard, Thomas ;
Iyer, Rathi V. ;
Rana, Sohail R. ;
Rogers, Zora R. ;
Sarnaik, Sharada A. ;
Thornburg, Courtney D. ;
Ware, Russell E. .
PEDIATRIC BLOOD & CANCER, 2012, 59 (04) :668-674
[4]   Fatigue in Adolescents and Young Adults With Sickle Cell Disease: Biological and Behavioral Correlates and Health-Related Quality of Life [J].
Ameringer, Suzanne ;
Elswick, R. K., Jr. ;
Smith, Wally .
JOURNAL OF PEDIATRIC ONCOLOGY NURSING, 2014, 31 (01) :6-17
[5]   Fatigue in Children With Sickle Cell Disease: Association With Neurocognitive and Social-Emotional Functioning and Quality of Life [J].
Anderson, Lindsay M. ;
Allen, Taryn M. ;
Thornburg, Courtney D. ;
Bonner, Melanie J. .
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2015, 37 (08) :584-589
[6]  
[Anonymous], 2006, The Barratt simplified measure of social status
[7]  
APA, 2013, Diagnostic and Statistical Manual of Mental Disorders: DSM-V, V5th
[8]   Nocturnal enuresis in pediatric sickle cell disease [J].
Barakat, LP ;
Smith-Whitley, K ;
Schulman, S ;
Rosenberg, D ;
Puri, R ;
Ohene-Frempong, K .
JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, 2001, 22 (05) :300-305
[9]   Sickle cell nephropathy: challenging the conventional wisdom [J].
Becker, Amy M. .
PEDIATRIC NEPHROLOGY, 2011, 26 (12) :2099-2109
[10]   The number of people with sickle-cell disease in the United States: National and state estimates [J].
Brousseau, David C. ;
Panepinto, Julie A. ;
Nimmer, Mark ;
Hoffmann, Raymond G. .
AMERICAN JOURNAL OF HEMATOLOGY, 2010, 85 (01) :77-78