Tools for adaptive immune receptor repertoire sequencing

被引:2
|
作者
Lees, William D. [1 ]
机构
[1] Birkbeck Coll, Inst Struct & Mol Biol, Malet St, London WC1E 7HX, England
关键词
Antibody repertoire sequencing; Immune receptor genes; AIRR-seq tools; Rep-seq tools; CLONALITY INFERENCE; T-CELL; IMMUNOGLOBULIN;
D O I
10.1016/j.coisb.2020.10.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tools for adaptive immune receptor repertoire (AIRR) sequencing continue to evolve rapidly, and, although some established frameworks are emerging, there are no complete solutions: it is necessary to select tools and build a customised pipeline. Emerging trends of interest include standards for data interchange, tools for single-cell sequencing, genotyping, and tools that make use of probabilistic and structural inferences to identify receptor sequences of interest.
引用
收藏
页码:86 / 92
页数:7
相关论文
共 50 条
  • [1] Antigen discovery tools for adaptive immune receptor repertoire research
    Bousbaine, Djenet
    Ploegh, Hidde L.
    CURRENT OPINION IN SYSTEMS BIOLOGY, 2020, 24 : 64 - 70
  • [2] IGHV allele similarity clustering improves genotype inference from adaptive immune receptor repertoire sequencing data
    Peres, Ayelet
    Lees, William D.
    Rodriguez, Oscar L.
    Lee, Noah Y.
    Polak, Pazit
    Hope, Ronen
    Kedmi, Meirav
    Collins, Andrew M.
    Ohlin, Mats
    Kleinstein, Steven H.
    Watson, Corey T.
    Yaari, Gur
    NUCLEIC ACIDS RESEARCH, 2023, 51 (16) : E86
  • [3] Profiling genes encoding the adaptive immune receptor repertoire with gAIRR Suite
    Lin, Mao-Jan
    Lin, Yu-Chun
    Chen, Nae-Chyun
    Luo, Allen Chilun
    Lai, Sheng-Kai
    Hsu, Chia-Lang
    Hsu, Jacob Shujui
    Chen, Chien-Yu
    Yang, Wei-Shiung
    Chen, Pei-Lung
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [4] Biological controls for standardization and interpretation of adaptive immune receptor repertoire profiling
    Truck, Johannes
    Eugster, Anne
    Barennes, Pierre
    Tipton, Christopher M.
    Prak, Eline T. Luning
    Bagnara, Davide
    Soto, Cinque
    Sherkow, Jacob S.
    Payne, Aimee S.
    Lefranc, Marie-Paule
    Farmer, Andrew
    Bostick, Magnolia
    Mariotti-Ferrandiz, Encarnita
    ELIFE, 2021, 10
  • [5] Human adaptive immune receptor repertoire analysis-Past, present, and future
    Nielsen, Sandra C. A.
    Boyd, Scott D.
    IMMUNOLOGICAL REVIEWS, 2018, 284 (01) : 9 - 23
  • [6] Reading the repertoire: Progress in adaptive immune receptor analysis using machine learning
    O'Donnell, Timothy J.
    Kanduri, Chakravarthi
    Isacchini, Giulio
    Limenitakis, Julien P.
    Brachman, Rebecca A.
    Alvarez, Raymond A.
    Haff, Ingrid H.
    Sandve, Geir K.
    Greiff, Victor
    CELL SYSTEMS, 2024, 15 (12) : 1168 - 1189
  • [7] Immune receptor repertoire for influenza haemagglutinin
    Thomas, DB
    Patera, A
    Graham, CM
    Smith, CA
    BIOSCIENCE REPORTS, 1995, 15 (06) : 481 - 492
  • [8] Deep sequencing of B cell receptor repertoire
    Kim, Daeun
    Park, Daechan
    BMB REPORTS, 2019, 52 (09) : 540 - 547
  • [9] Profiling the broad antibody diversity of lymphatic filariasis immune antibody repertoire by deep sequencing
    Lim, Chia Chiu
    Lim, Theam Soon
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 290
  • [10] Utility of Bulk T-Cell Receptor Repertoire Sequencing Analysis in Understanding Immune Responses to COVID-19
    Kockelbergh, Hannah
    Evans, Shelley
    Deng, Tong
    Clyne, Ella
    Kyriakidou, Anna
    Economou, Andreas
    Hoang, Kim Ngan Luu
    Woodmansey, Stephen
    Foers, Andrew
    Fowler, Anna
    Soilleux, Elizabeth J.
    DIAGNOSTICS, 2022, 12 (05)