Evaluation of Eucalyptus citriodora essential oil on goat gastrointestinal nematodes

被引：20

作者：

Freitas Macedo, Iara Tersia ^{[1
]}

Leal Bevilaqua, Claudia Maria ^{[1
]}

Beserra de Oliveira, Lorena Mayana ^{[1
]}

Fernandes Camurca-Vasconcelos, Ana Lourdes ^{[1
]}

Vieira, Luiz da Silva

Albano Amora, Sthenia dos Santos

机构：

[1] Univ Estadual Ceara UECE, Lab Doencas Parasitarias, Programa Posgrad Ciencias Vet, BR-60740000 Fortaleza, Ceara, Brazil

来源：

REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA | 2011年 / 20卷 / 03期

关键词：

Phytotherapy; anthelmintic; Haemonchus contortus; Trichostrongylus spp; toxicity; MULTIPLE ANTHELMINTIC RESISTANCE; ACTIVITY IN-VITRO; LARVICIDAL ACTIVITY; PLANTS; EXTRACTS; MONOTERPENOIDS;

D O I：

10.1590/S1984-29612011000300009

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Phytotherapy may be an alternative strategy for controlling gastrointestinal parasites. This study evaluated the anthclmintic efficacy of Eucalyptus citriodora essential oil (EcEO). The in vitro effects of EcEO were determined through testing the inhibition of egg hatching and larval development of Haemonchus contortus. EcEO was subjected to acute toxicity testing on mice, orally and intraperitoneally. The in vivo effects of EcEO were determined by the fecal egg count reduction Lest (FECRF) in goats infected with gastrointestinal nematodes. The results showed that 5.3 mg.mL(-1) EcEO inhibited egg hatching by 98.8% and 10.6 mg.mL(-1) EcEO inhibited H. contort us larval development by 99.71%. The lethal doses for 50% of the mice were 4153 and 622.8 mg.kg(-1), for acute toxicity orally and intraperitoneally. In the FECRT, the efficacy of EcEO and ivermectin was 66.25 and 79.16% respectively, on goat gastrointestinal nematodes eight days after treatment. EcEO showed in vitro and in vivo anthelmintic activity.

引用

页码：223 / 227

页数：5

共 35 条

[1]

Adams R., 2001, Identification of essential oil components by gas chromatography/quadrupole mass spectrometry

[2] In vitro screening of two Nigerian medicinal plants (Vernonia amygdalina and Annona senegalensis) for anthelmintic activity [J].

Alawa, CBI ;

Adamu, AM ;

Gefu, JO ;

Ajanusi, OJ ;

Abdu, PA ;

Chiezey, NP ;

Alawa, JN ;

Bowman, DD .

VETERINARY PARASITOLOGY, 2003, 113 (01) :73-81

[3]

[Anonymous], 2006, REV BIOL CIENC TERRA

[4] Ovicidal and larvicidal activity in vitro of Spigelia anthelmia Linn.: extracts on Haemonchus contortus [J].

Assis, LM ;

Bevilaqua, CML ;

Morais, SM ;

Vieira, LS ;

Costa, CTC ;

Souza, JAL .

VETERINARY PARASITOLOGY, 2003, 117 (1-2) :43-49

[5] In vitro activity of Peltophorum africanum Sond. (Fabaceae) extracts on the egg hatching and larval development of the parasitic nematode Trichostrongylus colubriformis [J].

Bizimenyera, E. S. ;

Githiori, J. B. ;

Eloff, J. N. ;

Swan, G. E. .

VETERINARY PARASITOLOGY, 2006, 142 (3-4) :336-343

[6] Anthelmintic activity of Lippia sidoides essential oil on sheep gastrointestinal nematodes [J].

Camurca-Vasconcelos, A. L. E. ;

Bevilaqua, C. M. L. ;

Morais, S. M. ;

Maciel, M. V. ;

Costa, C. T. C. ;

Macedo, I. T. F. ;

Oliveira, L. M. B. ;

Braga, R. R. ;

Silva, R. A. ;

Vieira, L. S. ;

Navarro, A. M. C. .

VETERINARY PARASITOLOGY, 2008, 154 (1-2) :167-170

[7]

Chagas A. C. de S., 2002, Brazilian Journal of Veterinary Research and Animal Science, V39, P247, DOI 10.1590/S1413-95962002000500006

[8]

Choi IH, 2007, RUSS J NEMATOL, V15, P35

[9] Correlation between chemical composition and antibacterial activity of essential oils of some aromatic medicinal plants growing in the Democratic Republic of Congo [J].

Cimanga, K ;

Kambu, K ;

Tona, L ;

Apers, S ;

De Bruyne, T ;

Hermans, N ;

Totté, J ;

Pieters, L ;

Vlietinck, AJ .

JOURNAL OF ETHNOPHARMACOLOGY, 2002, 79 (02) :213-220

[10]

Clarke E.G.C., 1977, Veterinary Toxicology, Casell and Collier, P268

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