In vitro antioxidant, antimicrobial, cytotoxic potential of gold and silver nanoparticles prepared using Embelia ribes

被引:44
作者
Dhayalan, Manikandan [1 ]
Denison, Michael Immanuel Jesse [2 ]
Jegadeeshwari, Anitha L. [1 ]
Krishnan, Kathiravan [2 ]
Gandhi, Nagendra N. [1 ]
机构
[1] Anna Univ, Alagappa Coll Technol, Dept Chem Engn, Madras, Tamil Nadu, India
[2] Univ Madras, Dept Biotechnol, Madras, Tamil Nadu, India
关键词
Green synthesis; gold nanoparticles; silver nanoparticles; seed extract; Embelia ribes; BANANA PEEL EXTRACT; GREEN SYNTHESIS; PLANT;
D O I
10.1080/14786419.2016.1166499
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
In recent years, the green synthesis of gold (GNPs) and silver (SNPs) nanoparticles has gained great interest among chemists and researchers. The present study reports an eco-friendly, cost-effective, rapid and easy method for the synthesis of gold and silver nanoparticles using the seed extract of Embelia ribes (SEEr) as capping and reducing agent. The synthesised GNPs and SNPs were characterised using the following techniques: UV-vis spectroscopy, DLS, HR-TEM, FT-IR and XRD. The free radical scavenging potential of GNPs and SNPs was measured by DPPH assay and Phosphomolybdenum assay. Further, the antimicrobial activity against two micro-organisms were tested using disc diffusion method and cytotoxicity of GNPs and SNPs was determined against MCF-7 cell lines at different concentrations by MTT assay. Both the GNPs and SNPs prepared from E. ribes comparatively showed promising results thereby proving their clinical importance. [GRAPHICS] .
引用
收藏
页码:465 / 468
页数:4
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