SEROLOGIC SURVEY OF HUMANS FOR FLAVIVIRUS WEST NILE IN SOUTHERN MORAVIA (CZECH REPUBLIC)

被引：5
作者：
Hubalek, Zdenek [1 ]
Kriz, Bohumir [2 ]
Halouzka, Jiri [1 ]
机构：
[1] Acad Sci, Inst Vertebrate Biol, Brno, Czech Republic
[2] Natl Inst Publ Hlth, Prague, Czech Republic
来源：
CENTRAL EUROPEAN JOURNAL OF PUBLIC HEALTH | 2011年 / 19卷 / 03期
关键词：
West Nile virus; Flavivirus; Moravia; Czech Republic; serosurvey; GROUP-B ARBOVIRUSES; CROSS-NEUTRALIZATION; VIRUS;
D O I：
10.21101/cejph.a3635
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
A serosurvey for West Nile virus (WNV) was carried out in 525 persons, using a plaque-reduction neutralization microtest (PRN mu T) with Vero cells and Egyptian topotype Eg-101 strain as test virus. The blood sera were collected in four South-Moravian districts (Hodonin 44 persons, Breclav 102 persons, Znojmo 170 persons, Jihlava 209 persons) of the Czech Republic in the years 1988 and 1989, and stored at -20 degrees C. Antibodies to WNV were detected in only three humans (0.6% seropositivity): one person each in the districts of Hodonin (2.3% persons positive), Breclav (1.0% positive) and Jihlava (0.5% positive), with the titres of 1:64, 1:32, and 1:32, respectively. All the three sera were negative for antibody to tick-borne encephalitis virus. The results indicate that activity of WNV in southern Moravia was very low before 1990.
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页码：131 / 133
页数：3
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