Surgical treatment of hidradenitis suppurativa: A retrospective study of 93 cases

被引:13
作者
Bordier-Lamy, F. [1 ]
Palot, J. -P. [2 ]
Vitry, F. [3 ]
Bernard, P. [1 ]
Grange, F. [1 ]
机构
[1] CHU Reims, Serv Dermatol, Hop Robert Debre, F-51092 Reims, France
[2] CHU Reims, Serv Chirurg Digest, F-51092 Reims, France
[3] CHU Reims, Ctr Rech Invest Clin & Methodol, F-51092 Reims, France
来源
ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE | 2008年 / 135卷 / 05期
关键词
hidradenitis suppurativa; surgery;
D O I
10.1016/j.annder.2008.02.016
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Introduction. - Hidradenitis suppurativa is a chronic disease, severe forms of which may be highly invalidating. Although wide surgery is usually considered the most effective curative therapy, few medical teams in France have extensive experience of this approach. Our aim was to evaluate the clinical history and the results of surgery in all patients operated with curative intent in an experienced centre. Patients and methods. - Medical records were reviewed for all patients operated between January 1985 and January 2007. In addition, the patients were contacted by telephone and/or letter and asked about their clinical history, the repercussions of their disease on their daily lives, postsurgical relapse and their overall satisfaction regarding surgery. Separate analyses were carried out for patients and for individual operated sites. Results. - Of 93 patients followed-up for between one and 205 months (mean: 30 months), 209 anatomical sites were operated with curative intent, using either limited excision (i.e. including all visible lesions without margins) or wide excision (i.e. including all lesions with a significant margin). The disease had been present for an average of 7.6 years before surgical treatment, with onset seven years earlier in women. Most patients had previously received multiple and often unsuitable medical treatments. Patients' personal and professional lives were highly affected. Surgery required hospitalization for an average duration of 6.6 days, caused complications in 21% of cases and was often perceived as trying. Relapse in the operated areas occurred in 33% of cases and this was more frequent after limited excision. Nevertheless, 74% of patients were ultimately satisfied with their surgical treatment and most regarded surgery as the only realty effective therapy. Discussion. - Our study confirms the heavy repercussions of hidradenitis suppurativa, on patients' day-life as well as the value of surgical management by experienced surgeons. Conclusion. - Wide excision remains the mainstay of therapy in extensive forms of hidradenitis suppurativa. However, this chronic, disseminated and recurrent disease continues to be insufficiently understood and innovative medical approaches, including the development of clinical trials, are required. (c) 2008 Elsevier Masson SAS. Tous droits reserves.
引用
收藏
页码:373 / 379
页数:7
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