Prevalence of Staphylococcus aureus carrying Panton-Valentine leukocidin genes among isolates from hospitalised patients in China

被引：131

作者：

Yu, F. ^{[1
]}

Chen, Z. ^{[1
]}

Liu, C. ^{[1
]}

Zhang, X. ^{[1
]}

Lin, X. ^{[1
]}

Chi, S. ^{[1
]}

Zhou, T. ^{[1
]}

Chen, Z. ^{[1
]}

Chen, X. ^{[1
]}

机构：

[1] Whenzhou Med Coll, Affiliated Hosp 1, Dept Lab Med, Wenzhou 325000, Peoples R China

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2008年 / 14卷 / 04期

关键词：

China; methicillin resistance; Panton-Valentine leukocidin; prevalence; sequence types; Staphylococcus aureus;

D O I：

10.1111/j.1469-0691.2007.01927.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Between January 2005 and January 2006, 25 (12.8%) of 195 Staphylococcus aureus isolates were positive for Panton-Valentine leukocidin (PVL) genes in a teaching hospital in Wenzhou, China. Nineteen (11.9%) of 160 hospital-acquired isolates, and six (17.1%) of 35 community-acquired isolates, harboured lukS/F-PV. Six sequence types (ST88, ST239, ST398, ST25, ST30 and ST59) were found among 18 PVL-positive methicillin-resistant isolates with SCCmec types I, III, IIIA or IV. Only ST88 was found among seven PVL-positive methicillin-susceptible S. aureus isolates. The PVL-positive isolates were associated with lung infection, bloodstream infection and soft-tissue pyogenic infection. Overall, there was a high prevalence of PVL genes in genetically diverse S. aureus isolates.

引用

页码：381 / 384

页数：4

共 20 条

[1] Molecular characterization of methicillin-resistant Staphylococcus aureus bloodstream isolates from Croatia [J].

Budimir, A ;

Deurenberg, RH ;

Plecko, V ;

Vink, C ;

Kalenic, S ;

Stobberingh, EE .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 57 (02) :331-334

[2]

Cirlan Maria, 2005, Infection Genetics and Evolution, V5, P335, DOI 10.1016/j.meegid.2004.09.005

[3]

Clinical and Laboratory Standards Institute, 2006, PERF STAND ANT SUSC, P44

[4] Polyclonal emergence and importation of community-acquired methicillin-resistant Staphylococcus aureus strains harbouring Panton-Valentine leucocidin genes in Belgium [J].

Denis, O ;

Deplano, A ;

De Beenhouwer, H ;

Hallin, M ;

Huysmans, G ;

Garrino, MG ;

Glupczynski, Y ;

Malaviolle, X ;

Vergison, A ;

Struelens, MJ .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (06) :1103-1106

[5] Widespread skin and soft-tissue infections due to two methicillin-resistant Staphylococcus aureus strains harboring the genes for Panton-Valentine leucocidin [J].

Diep, BA ;

Sensabaugh, GF ;

Somboona, NS ;

Carleton, HA ;

Perdreau-Remington, F .

JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (05) :2080-2084

[6] Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus [J].

Enright, MC ;

Day, NPJ ;

Davies, CE ;

Peacock, SJ ;

Spratt, BG .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (03) :1008-1015

[7]

GILBERT M, 2005, CAN J INFECT DIS MED, V16, P109

[8] Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients [J].

Gillet, Y ;

Issartel, B ;

Vanhems, P ;

Fournet, JC ;

Lina, G ;

Bes, M ;

Vandenesch, F ;

Piémont, Y ;

Brousse, N ;

Floret, D ;

Etienne, J .

LANCET, 2002, 359 (9308) :753-759

[9] Severe staphylococcal sepsis in adolescents in the era of community-acquired methicillin-resistant Staphylococcus aureus [J].

Gonzalez, BE ;

Martinez-Aguilar, G ;

Hulten, KG ;

Hammerman, WA ;

Coss-Bu, J ;

Avalos-Mishaan, A ;

Mason, EO ;

Kaplan, SL .

PEDIATRICS, 2005, 115 (03) :642-648

[10] Community-associated strains of methicillin-resistant Staphylococccus aureus as the cause of healthcare-associated infection [J].

Gonzalez, Blanca E. ;

Rueda, Adriana M. ;

Shelburne, Samuel A., III ;

Musher, Daniel M. ;

Hamill, Richard J. ;

Hulten, Kristina G. .

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2006, 27 (10) :1051-1056

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