Plasma Ropivacaine levels during awake intracranial surgery

被引：9
作者：
Audu, PB
Wilkerson, C
Bartkowski, R
Gingrich, K
Viscusi, E
Andrews, D
机构：
[1] Thomas Jefferson Univ, Jefferson Med Coll, Dept Anesthesiol, Philadelphia, PA 19107 USA
[2] Thomas Jefferson Univ, Jefferson Med Coll, Dept Neurosurg, Philadelphia, PA 19107 USA
来源：
JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY | 2005年 / 17卷 / 03期
关键词：
awake craniotomy; local anesthetic toxicity; ropivacaine;
D O I：
10.1097/01.ana.0000167446.56839.a4
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Plasma ropivacaine levels produced by routine scalp infiltration for field block were assayed in eight patients undergoing awake intracranial surgery. Levels peaked within approximately 13 minutes, indicating rapid systemic absorption of ropivacaine. Potentially toxic plasma drug levels were achieved in three of eight patients, although no untoward effects attributable to elevated levels of ropivacaine were observed. Clinical vigilance is indicated during scalp infiltration with ropivacaine.
引用
收藏
页码：153 / 155
页数：3
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