Age-specific prevalence of dengue antibodies in Bangkok infants and children

被引：13

作者：

Pengsaa, Krisana ^{[1
]}

Limkittikul, Kriengsak ^{[1
]}

Luxemburger, Christine ^{[2
]}

Yoksan, Sutee ^{[3
]}

Chambonneau, Laurent ^{[2
]}

Ariyasriwatana, Churdchoo ^{[4
]}

Lapphra, Keswadee ^{[1
]}

Chanthavanich, Pornthep ^{[1
]}

Lang, Jean ^{[2
]}

Sabchareon, Arunee ^{[1
]}

机构：

[1] Mahidol Univ, Fac Trop Med, Dept Trop Pediat, Bangkok, Thailand

[2] Sanofi Pasteur, Lyon, France

[3] Mahidol Univ, Inst Sci & Technol Res & Dev, Ctr Vaccine Dev, Nakhon Pathom, Thailand

[4] Minist Publ Hlth, Queen Sirikit Natl Inst Child Hlth, Bangkok, Thailand

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2008年 / 27卷 / 05期

关键词：

dengue antibody; infants; dengue infection;

D O I：

10.1097/INF.0b013e3181646d45

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Seroprevalence of dengue antibodies were determined in healthy children in Bangkok. At 9, 12, and 18 months of age 23%, 9%, and 17% of children respectively had neutralizing antibodies against one or more serotypes. DEN1 was the most prevalent, followed by DEN3, DEN2, and DEN4. Twelve children had serologic evidence of dengue infection. The nadir of dengue antibodies in children was at 12 months of age. In highly endemic areas, dengue vaccination could be needed at an early age.

引用

页码：461 / 463

页数：3

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