Relationship Type and Use of the Vaginal Ring for HIV-1 Prevention in the MTN 020/ASPIRE Trial

被引:9
作者
Pleasants, E. [1 ]
Tauya, T. [2 ]
Reddy, K. [3 ]
Mirembe, B. G. [4 ]
Woeber, K. [5 ]
Palanee-Phillips, T. [3 ]
Zimba, C. [6 ,7 ]
Atujuna, M. [8 ]
Montgomery, E. T. [1 ]
Baeten, Jared [9 ]
Palanee-Phillips, Thesla [10 ,20 ,21 ]
Brown, Elizabeth [11 ]
Soto-Torres, Lydia [12 ]
Schwartz, Katie [13 ]
Makanani, Bonus [14 ,15 ]
Martinson, Francis [16 ]
Bekker, Linda-Gail [17 ]
Govender, Vaneshree [18 ]
Siva, Samantha [18 ]
Gaffoor, Zakir [18 ]
Naidoo, Logashvari [18 ]
Pather, Arendevi [18 ]
Jeenarain, Nitesha [18 ]
Nair, Gonasagrie [19 ]
Palanee-Phillips, Thesla [10 ,20 ,21 ]
Matovu, Flavia [22 ]
Mgodi, Nyaradzo [23 ]
Mhlanga, Felix [24 ]
机构
[1] UC Berkeley SPH, RTI Int, Womens Global Hlth Imperat, 628 Beacon St, Oakland, CA 94610 USA
[2] Univ Zimbabwe Univ Calif San Francisco Collaborat, San Francisco, CA USA
[3] Univ Witwatersrand, Wits Reprod Hlth & HIV Inst Wits RHI, Johannesburg, South Africa
[4] Makerere Univ Johns Hopkins Univ Res Collaborat M, Kampala, Uganda
[5] SAMRC, HIV Prevent Res Unit, Cape Town, South Africa
[6] Tidziwe Ctr, UNC Project, Lilongwe, Malawi
[7] Kamuzu Cent Hosp, Lilongwe, Malawi
[8] Univ Cape Town, Desmond Tutu HIV Fdn, DTHC, Cape Town, South Africa
[9] Univ Washington, Seattle, WA 98195 USA
[10] Wits Reprod Hlth & HIV Inst, Johannesburg, South Africa
[11] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA
[12] US NIAID, Bethesda, MD USA
[13] FHI 360, Durham, NC USA
[14] Johns Hopkins Univ, Queen Elizabeth Hosp, Baltimore, MD 21218 USA
[15] Queen Elizabeth Hosp, London, England
[16] Univ N Carolina, Chapel Hill, NC 27515 USA
[17] Univ Cape Town, Cape Town, South Africa
[18] South African Med Res Council, Durban, South Africa
[19] Ctr AIDS Programme Res South Africa, Durban, South Africa
[20] Wits RHI, Johannesburg, South Africa
[21] Johns Hopkins Univ, Baltimore, MD 21218 USA
[22] Makerere Univ, Kampala, Uganda
[23] Univ Zimbabwe, Coll Hlth Sci, Clin Trials Unit, Chitungwiza, Zimbabwe
[24] Univ Zimbabwe, Coll Hlth Sci, Clin Trials Unit, Harare, Zimbabwe
关键词
Gender; HIV; Clinical trial; Vaginal ring; Sexual relationship; Sub-Saharan Africa; Women; Microbicide; Qualitative research; Gender relations; Couples; Adherence; Female controlled HIV prevention; TOPICAL MICROBICIDES; RELATIONSHIP POWER; AGE-DIFFERENCES; SOUTH-AFRICA; ACCEPTABILITY; RISK; DYNAMICS; WOMEN; CONTEXT; SEXUALITY;
D O I
10.1007/s10461-019-02521-9
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Gender roles and imbalances in sexual power contribute to the heightened HIV-1 risk faced by women in Sub-Saharan Africa. This has led prevention research to focus on the development of female controlled methods. Despite the design of products such as vaginal rings to be used autonomously by women, male partners and women's perceptions of relationships influence HIV prevention choices. To understand the influences that male partners and dyadic dynamics had on the use of the Dapivirine Vaginal Ring in the ASPIRE trial, this analysis of qualitative data explored the types of intimate partner relationships that women engaged in. This paper describes how partners facilitated or challenged women's ring use and how women dealt with these challenges within six different types of relationships characterized by power dynamics and commitment levels. We offer insights into how future use of female-initiated HIV prevention products can be promoted through recognition of different relationship types.
引用
收藏
页码:866 / 880
页数:15
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