Contemporary Management of Pineoblastoma

被引：24

作者：

Tate, Matthew C. ^{[1
]}

Rutkowski, Martin J. ^{[1
]}

Parsa, Andrew T. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94117 USA

来源：

NEUROSURGERY CLINICS OF NORTH AMERICA | 2011年 / 22卷 / 03期

关键词：

Pineoblastoma; Survival; Treatment; PINEAL REGION TUMORS; PARENCHYMAL TUMORS; SURVIVAL; ADULTS; BRAIN;

D O I：

10.1016/j.nec.2011.05.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Pineoblastomas (PBs) represent the most aggressive of the pineal parenchymal tumors. Routine treatment consists of operative management of obstructive hydrocephalus and cerebrospinal fluid studies followed by maximal resection and adjuvant chemotherapy/radiotherapy, resulting in a median survival of 20 months. Important prognostic factors for survival of patients with PB include extent of resection, age at presentation, disseminated disease, and craniospinal radiotherapy. Novel strategies being evaluated for the treatment of PB include high-dose chemotherapy with autologous stem cell therapy, stereotactic radiosurgery, and histone deacetylase inhibitors.

引用

页码：409 / +

页数：5

共 21 条

[1] SURGICAL-MANAGEMENT OF PINEAL REGION TUMORS [J].

BRUCE, JN ;

STEIN, BM .

ACTA NEUROCHIRURGICA, 1995, 134 (3-4) :130-135

[2]

CHANG SM, 1995, NEUROSURGERY, V37, P383, DOI 10.1227/00006123-199509000-00003

[3] Pineal Tumors [J].

Dahiya, Sonika ;

Perry, Arie .

ADVANCES IN ANATOMIC PATHOLOGY, 2010, 17 (06) :419-427

[4] Response of an adult patient with pineoblastoma to vorinostat and retinoic acid [J].

DeBoer, Rebecca ;

Batjer, Hunt ;

Marymont, Maryanne ;

Goldman, Stewart ;

Walker, Matthew ;

Gottardi-Littell, Numa ;

Raizer, Jeffrey .

JOURNAL OF NEURO-ONCOLOGY, 2009, 95 (02) :289-292

[5] Parenchymal pineal tumors: A clinicopathological study of 76 cases [J].

Fauchon, F ;

Jouvet, A ;

Paquis, P ;

Saint-Pierre, G ;

Mottolese, C ;

Ben Hassel, M ;

Chauveinc, L ;

Sichez, JP ;

Philippon, J ;

Schlienger, M ;

Bouffet, E .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2000, 46 (04) :959-968

[6] Microarray analysis reveals differential gene expression patterns in tumors of the pineal region [J].

Fevre-Montange, Michelle ;

Champier, Jacques ;

Szathmari, Alexandru ;

Wierinckx, Anne ;

Mottolese, Carmine ;

Guyotat, Jacques ;

Figarella-Branger, Dominique ;

Jouvet, Anne ;

Lachuer, Joel .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2006, 65 (07) :675-684

[7] Comprehensive assessment of hemorrhage risks and outcomes after stereotactic brain biopsy [J].

Field, P ;

Witham, TF ;

Flickinger, JC ;

Kondziolka, D ;

Lunsford, LD .

JOURNAL OF NEUROSURGERY, 2001, 94 (04) :545-551

[8] Outcome of pediatric pineoblastoma after surgery, radiation and chemotherapy [J].

Gilheeney, Stephen W. ;

Saad, Ali ;

Chi, Susan ;

Turner, Christopher ;

Ullrich, Nicole J. ;

Goumnerova, Liliana ;

Scott, R. Michael ;

Marcus, Karen ;

Lehman, Leslie ;

De Girolami, Umberto ;

Kieran, Mark W. .

JOURNAL OF NEURO-ONCOLOGY, 2008, 89 (01) :89-95

[9]

HART MN, 1973, CANCER, V32, P890, DOI 10.1002/1097-0142(197310)32:4<890::AID-CNCR2820320421>3.0.CO

[10]

2-O

← 1 2 3 →