Lenalidomide-mediated erythroid improvement in non-del(5q) myelodysplastic syndromes is associated with bone marrow immuno-remodeling

被引:6
|
作者
Kerdivel, G. [1 ,2 ,3 ,4 ,5 ]
Chesnais, V. [1 ,2 ,3 ,4 ,6 ]
Becht, E. [4 ,7 ,8 ]
Toma, A. [9 ]
Cagnard, N. [10 ]
Dumont, F. [1 ,2 ,3 ,4 ,11 ]
Rousseau, A. [12 ]
Fenaux, P. [13 ]
Chevret, S. [14 ]
Chapuis, N. [1 ,2 ,3 ,4 ,6 ,12 ]
Boeva, V. [1 ,2 ,3 ,4 ,5 ]
Fridman, W. H. [4 ,7 ]
Fontenay, M. [1 ,2 ,3 ,4 ,6 ,12 ]
Kosmider, O. [1 ,2 ,3 ,4 ,6 ,12 ]
机构
[1] Inst Cochin, Dept Dev, Reprod, Canc, Paris, France
[2] INSERM, U1016, Paris, France
[3] CNRS, UMR8104, Paris, France
[4] Univ Paris 05, Paris, France
[5] Team Computat Epigenet Canc, Paris, France
[6] Team Normal & Pathol Hematopoiesis Labeled Ligue, Paris, France
[7] INSERM UMR S1138, Canc Immune Controls & Escape, Cordeliers Res Ctr, Paris, France
[8] ASTAR, Singapore Immunol Network, Singapore, Singapore
[9] Hop Henri Mondor, AP HP, Serv Hematol Clin & Therapie Cellulaire, Creteil, France
[10] Univ Paris 05, Plateforme Paris Descartes Bioinformat, Paris, France
[11] Inst Cochin, Plateforme Genom, Paris, France
[12] Hop Cochin, AP HP, Serv Hematol Biol, Paris, France
[13] Hop St Louis, AP HP, Serv Hematol Senior, Paris, France
[14] Hop St Louis, AP HP, Lab Biostat & Epidemiol Clin INSERM UMR S 717, Paris, France
关键词
TRANSFUSION-DEPENDENT PATIENTS; 5Q DELETION; RISK MDS; ERYTHROPOIETIN; PLACEBO;
D O I
10.1038/leu.2017.305
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:558 / 562
页数:6
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