Complement receptor 3 binds the Borrelia burgdorferi outer surface proteins OspA and OspB in an iC3b-independent manner

被引：19
作者：
Garcia, RC
Murgia, R
Cinco, M
机构：
[1] ICGEB, Leukocyte Biol Unit, I-34012 Trieste, Italy
[2] Univ Trieste, Dipartimento Sci Biomed, I-34127 Trieste, Italy
来源：
INFECTION AND IMMUNITY | 2005年 / 73卷 / 09期
关键词：
D O I：
10.1128/IAI.73.9.6138-6142.2005
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Persistence of borreliae within the vertebrate host depends on the fate of interactions between the spirochetes and target cells. The present work demonstrates the direct binding of the Borrelia burgdorferi outer surface proteins OspA and OspB to CR3 and that this binding is independent of iC3b.
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收藏
页码：6138 / 6142
页数：5
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