A review of clinical and histological parameters associated with contralateral neck metastases in oral squamous cell carcinoma

被引：95

作者：

Fan, Song ^{[1
]}

Tang, Qiong-lan ^{[2
]}

Lin, Ying-jin ^{[3
]}

Chen, Wei-liang ^{[1
]}

Li, Jin-song ^{[1
]}

Huang, Zhi-quan ^{[1
]}

Yang, Zhao-hui ^{[1
]}

Wang, You-yuan ^{[1
]}

Zhang, Da-ming ^{[1
]}

Wang, Hui-jing ^{[1
]}

Dias-Ribeiro, Eduardo ^{[4
]}

Cai, Qiang ^{[1
]}

Wang, Lei ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Affiliated Hosp 2, Sun Yet Sen Mem Hosp, Dept Oral & Maxillofacial Surg, Guangzhou 510120, Peoples R China

[2] Sun Yat Sen Univ, Affiliated Hosp 2, Sun Yet Sen Mem Hosp, Dept Pathol, Guangzhou 510120, Peoples R China

[3] Guangzhou Med Univ, Affiliated Hosp 1, Dept Neurol, Guangzhou 510120, Peoples R China

[4] Centro Univ Joao Pessoa, Fac Dent, BR-1602 Joao Pessoa, Paraiba, Brazil

来源：

INTERNATIONAL JOURNAL OF ORAL SCIENCE | 2011年 / 3卷 / 04期

关键词：

oral squamous cell carcinoma; lymph node metastasis; contralateral neck metastasis; neck dissection; head and neck cancer; LYMPH-NODE METASTASIS; UPPER AERODIGESTIVE TRACT; PROGNOSTIC-FACTORS; STAGE-I; TONGUE CARCINOMA; TUMOR THICKNESS; N0; NECK; OROPHARYNGEAL CARCINOMA; EPIDERMOID CARCINOMA; EXTRACAPSULAR SPREAD;

D O I：

10.4248/IJOS11068

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Oral squamous cell carcinoma (OSCC) has a high incidence of cervical micrometastases and sometimes metastasizes contralaterally because of the rich lymphatic intercommunications relative to submucosal plexus of oral cavity that freely communicate across the midline, and it can facilitate the spread of neoplastic cells to any area of the neck consequently. Clinical and histopathologic factors continue to provide predictive information to contralateral neck metastases (CLNM) in OSCC, which determine prophylactic and adjuvant treatments for an individual patient. This review describes the predictive value of clinical-histopathologic factors, which relate to primary tumor and cervical lymph nodes, and surgical dissection and adjuvant treatments. In addition, the indications for elective contralateral neck dissection and adjuvant radiotherapy (aRT) and strategies for follow-up are offered, which is strongly focused by clinicians to prevent later CLNM and poor prognosis subsequently.

引用

页码：180 / 191

页数：12

共 120 条

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