Iodine catalyzed one-pot synthesis of 3,4-dihydroquinazolin-4-ones from anthranilic acids, ortho esters and amines under solvent-free conditions

被引：19

作者：

Wang Hong-She ^{[1
]}

Zeng Jun-E ^{[1
]}

机构：

[1] Baoji Univ Arts & Sci, Dept Chem & Chem Engn, Shaaxi Key Lab Phytochem, Baoji 721007, Shaanxi, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2008年 / 26卷 / 01期

关键词：

iodine; 3,4-dihydroquinazolin-4-one; one-pot reaction; catalysis;

D O I：

10.1002/cjoc.200890017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and efficient procedure has been developed for the one-pot synthesis of 3,4-dihydroquinazolin-4-ones from anthranilic acids, ortho esters and amines using a catalytic amount of iodine under solvent-free conditions to afford the corresponding products in excellent yields. The direct use of commercially available catalyst, mild and solvent-free reaction conditions, short reaction time, easy workup and excellent yields are the advantages of the present protocol.

引用

页码：175 / 178

页数：4

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