Red-emissive triplex-forming PNA probes carrying cyanine base surrogates for fluorescence sensing of double-stranded RNA

被引：29

作者：

Chiba, Toshiki ^{[1
]}

Sato, Takaya ^{[1
]}

Sato, Yusuke ^{[1
]}

Nishizawa, Seiichi ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Sendai, Miyagi 9808578, Japan

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2017年 / 15卷 / 37期

关键词：

PEPTIDE NUCLEIC-ACIDS; PHYSIOLOGICALLY RELEVANT CONDITIONS; NUCLEOBASE-MODIFIED PNA; THIAZOLE ORANGE; FIT-PROBES; HELICAL RECOGNITION; CIRCULAR-DICHROISM; DNA INTERACTIONS; BINDING; DUPLEXES;

D O I：

10.1039/c7ob02077e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Red-emissive fluorescent probes have been developed by integration of quinoline blue or thiazole red as the base surrogate into triplex-forming PNAs, allowing selective sensing of a sequence of double-stranded RNA.

引用

收藏

页码：7765 / 7769

页数：5

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