Early administration of branched-chain amino acid granules

被引：14

作者：

Ishikawa, Toru ^{[1
]}

机构：

[1] Saiseikai Niigata Daini Hosp, Dept Gastroenterol & Hepatol, Niigata 9501104, Japan

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2012年 / 18卷 / 33期

关键词：

Branched-chain amino acid to tyrosine ratio; Branched-chain amino acid granules; Liver cirrhosis; Nutritional intervention; Malnutrition; Quality of life; Albumin; Cancer onset; CHRONIC LIVER-DISEASE; SERUM-ALBUMIN LEVEL; EVENT-FREE SURVIVAL; HEPATITIS-C VIRUS; HEPATOCELLULAR-CARCINOMA; RADIOFREQUENCY ABLATION; ORAL SUPPLEMENTATION; RANDOMIZED-TRIAL; CIRRHOSIS; CHEMOEMBOLIZATION;

D O I：

10.3748/wjg.v18.i33.4486

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The effect of malnutrition on survival in patients with decompensated liver cirrhosis has not been well defined. Nutritional intervention with branched-chain amino acid (BCAA) can increase serum albumin concentration in patients with decompensated cirrhosis but its effects on survival are unclear. The BCAA to tyrosine ratio (BTR) is a surrogate marker (the normal range of BTR is between 4.41 and 10.05, and a Fischer's ratio of 1.8 corresponds to a BTR of 3.5) in patients with decompensated liver cirrhosis, and BCAA inhibits hepatic carcinogenesis in patients with compensated cirrhosis. This review discusses data regarding the effect of early administration of BCAA granules based on the ratio of BCAA to BTR on prognosis in patients with cirrhosis. (C) 2012 Baishideng. All rights reserved.

引用

页码：4486 / 4490

页数：5

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