Effects of Digoxin in Heart Failure (HF) With Reduced Ejection Fraction (EF)

被引：7

作者：

Parikh, Riya R. ^{[1
]}

Patel, Khushbu R. ^{[1
]}

Pergolizzi, Joseph, V ^{[2
]}

Breve, Frank ^{[1
]}

Magnusson, Peter ^{[3
,4
]}

机构：

[1] Temple Univ, Dept Pharm, Philadelphia, PA 19122 USA

[2] Nat Cardio Inc, Cardiol, Naples, FL USA

[3] Orebro Univ, Sch Med Sci, Cardiol, Orebro, Sweden

[4] Karolinska Inst, Cardiol Res Unit, Med, Stockholm, Sweden

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2022年 / 14卷 / 03期

关键词：

cv; cardiovascular; readmission; rehospitalization; mortality; reduced ejection fraction; digitalis; heart failure; digoxin; hfref; OUTCOMES; RISK; BORDERLINE; GUIDELINES;

D O I：

10.7759/cureus.22778

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this review, we evaluated the literature on the benefits and deleterious effects of digoxin in heart failure (HF) with reduced ejection fraction (EF). Although digoxin was considered an effective treatment for HF, the supporting evidence is conflicting. Before the conventional use of modern HF therapies, digoxin was widely used for symptomatic relief on these patients. Further randomized trials are required to reach a definite conclusion about its efficacy and safety in patients experiencing HF with a reduced EF (HFrEF).

引用

页数：5

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