Rapid and efficient methodology to perform macrocyclization reactions in solid-phase peptide chemistry

被引：21

作者：

Grieco, P ^{[1
]}

Campiglia, P ^{[1
]}

Gomez-Monterrey, I ^{[1
]}

Lama, T ^{[1
]}

Novellino, E ^{[1
]}

机构：

[1] Univ Naples Federico II, Dipartimento Chim Farmaceut & Tossicol, I-80131 Naples, Italy

来源：

SYNLETT | 2003年 / 14期

关键词：

solid-phase peptide synthesis; macrocyclization; microwave synthesis;

D O I：

10.1055/s-2003-42054

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Solid-phase peptide synthesis and microwave-assisted organic synthesis have been combined in order to speed up drug discovery process of macrocyclization products in high purity and good yield.

引用

页码：2216 / 2218

页数：3

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