Evaluation of the LINX antireflux procedure

被引:9
作者
Sheu, Eric G. [1 ,2 ]
Rattner, David W. [2 ,3 ]
机构
[1] Brigham & Womens Hosp, Dept Surg, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
[3] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA
关键词
gastroesophageal reflux disease; LINX device; magnetic sphincter augmentation; GASTROESOPHAGEAL-REFLUX DISEASE; MAGNETIC SPHINCTER AUGMENTATION; NISSEN FUNDOPLICATION; ANGELCHIK PROSTHESIS; TERM OUTCOMES; DEVICE; FEASIBILITY; SAFETY; TRIAL; GERD;
D O I
10.1097/MOG.0000000000000189
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Purpose of review To evaluate the current data on the safety, efficacy, and indications for magnetic sphincter augmentation (MSA) using the LINX device to treat gastroesophageal reflux disease (GERD). Recent findings The LINX device has demonstrated excellent safety and GERD efficacy in several recent nonblinded, single arm studies with strict inclusion criteria and up to 3 years follow-up. Dysphagia has been the most common adverse effect occurring after LINX. Other gastrointestinal side-effects seen after laparoscopic fundoplication (bloating, gas, and inability to belch) may be less common after LINX. Summary The LINX device is a safe, well tolerated, and effective therapy for GERD in the short term. MSA should be considered for selected GERD patients without significant anatomic or motility defects. However, the long-term safety and efficacy of LINX - both alone and in comparison to current GERD therapies - remains to be determined.
引用
收藏
页码:334 / 338
页数:5
相关论文
共 15 条
[1]   One Hundred Consecutive Patients Treated with Magnetic Sphincter Augmentation for Gastroesophageal Reflux Disease: 6 Years of Clinical Experience from a Single Center [J].
Bonavina, Luigi ;
Saino, Greta ;
Bona, Davide ;
Sironi, Andrea ;
Lazzari, Veronica .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2013, 217 (04) :577-585
[2]   Laparoscopic Sphincter Augmentation Device Eliminates Reflux Symptoms and Normalizes Esophageal Acid Exposure One- and 2-Year Results of a Feasibility Trial [J].
Bonavina, Luigi ;
DeMeester, Tom ;
Fockens, Paul ;
Dunn, Daniel ;
Saino, Greta ;
Bona, Davide ;
Lipham, John ;
Bemelman, Willem ;
Ganz, Robert A. .
ANNALS OF SURGERY, 2010, 252 (05) :857-862
[3]   Magnetic Augmentation of the Lower Esophageal Sphincter: Results of a Feasibility Clinical Trial [J].
Bonavina, Luigi ;
Saino, Greta I. ;
Bona, Davide ;
Lipham, John ;
Ganz, Robert A. ;
Dunn, Daniel ;
DeMeester, Tom .
JOURNAL OF GASTROINTESTINAL SURGERY, 2008, 12 (12) :2133-2140
[4]   Use of a magnetic sphincter for the treatment of GERD: a feasibility study [J].
Ganz, Robert A. ;
Gostout, Christopher J. ;
Grudem, Jerry ;
Swanson, William ;
Berg, Todd ;
DeMeester, Tom R. .
GASTROINTESTINAL ENDOSCOPY, 2008, 67 (02) :287-294
[5]  
Ganz RA, 2013, NEW ENGL J MED, V368, P2039, DOI [10.1056/NEJMoa1205544, 10.1056/NEJMc1303656]
[6]   Magnetic lower esophageal sphincter augmentation device removal [J].
Harnsberger, Cristina R. ;
Broderick, Ryan C. ;
Fuchs, Hans F. ;
Berducci, Martin ;
Beck, Catherine ;
Gallo, Alberto ;
Jacobsen, Garth R. ;
Sandler, Bryan J. ;
Horgan, Santiago .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2015, 29 (04) :984-986
[7]   Long-term Outcomes of Laparoscopic Adjustable Gastric Banding [J].
Himpens, Jacques ;
Cadiere, Guy-Bernard ;
Bazi, Michel ;
Vouche, Michael ;
Cadiere, Benjamin ;
Dapri, Giovanni .
ARCHIVES OF SURGERY, 2011, 146 (07) :802-807
[8]   Safety analysis of first 1000 patients treated with magnetic sphincter augmentation for gastroesophageal reflux disease [J].
Lipham, J. C. ;
Taiganides, P. A. ;
Louie, B. E. ;
Ganz, R. A. ;
DeMeester, T. R. .
DISEASES OF THE ESOPHAGUS, 2015, 28 (04) :305-311
[9]   The LINX® reflux management system: confirmed safety and efficacy now at 4 years [J].
Lipham, John C. ;
DeMeester, Tom R. ;
Ganz, Robert A. ;
Bonavina, Luigi ;
Saino, Greta ;
Dunn, Daniel H. ;
Fockens, Paul ;
Bemelman, Willem .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2012, 26 (10) :2944-2949
[10]   Short-Term Outcomes Using Magnetic Sphincter Augmentation Versus Nissen Fundoplication for Medically Resistant Gastroesophageal Reflux Disease [J].
Louie, Brian E. ;
Farivar, Alexander S. ;
Shultz, Dale ;
Brennan, Christina ;
Vallieres, Eric ;
Aye, Ralph W. .
ANNALS OF THORACIC SURGERY, 2014, 98 (02) :498-505