Neuroanatomy and physiology of colorectal function and defaecation: from basic science to human clinical studies

被引：40

作者：

Brookes, S. J. ^{[1
,2
]}

Dinning, P. G. ^{[3
]}

Gladman, M. A. ^{[4
]}

机构：

[1] Flinders Univ S Australia, Dept Human Physiol, Adelaide, SA 5001, Australia

[2] Flinders Univ S Australia, Ctr Neurosci, Adelaide, SA 5001, Australia

[3] Univ New S Wales, St George Hosp, Dept Med, Sydney, NSW, Australia

[4] Queen Mary Univ London, Barts & London Sch Med & Dent, London, England

来源：

NEUROGASTROENTEROLOGY AND MOTILITY | 2009年 / 21卷

基金：

澳大利亚国家健康与医学研究理事会;

关键词：

Colorectal neuranatomy and physiology; control of defaecation; functional constipation; COLONIC MOTOR-ACTIVITY; CANINE PROXIMAL COLON; PIG SMALL-INTESTINE; GUINEA-PIG; ANORECTAL FUNCTION; CIRCULAR MUSCLE; IMMUNOHISTOCHEMICAL CHARACTERIZATION; GASTROINTESTINAL-TRACT; INTRAGANGLIONIC LAMINAR; OBSTRUCTED DEFECATION;

D O I：

10.1111/j.1365-2982.2009.01400.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

P>Colorectal physiology is complex and involves programmed, coordinated interaction between muscular and neuronal elements. Whilst a detailed understanding remains elusive, novel information has emerged from recent basic science and human clinical studies concerning normal sensorimotor mechanisms and the organization and function of the key elements involved in the control of motility. This chapter summarizes these observations to provide a contemporary review of the neuroanatomy and physiology of colorectal function and defaecation.

引用

页码：9 / 19

页数：11

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