Molecular basis of mechanosensory transduction

被引：521

作者：

Gillespie, PG ^{[1
]}

Walker, RG

机构：

[1] Oregon Hlth Sci Univ, Oregon Hearing Res Ctr, Portland, OR 97201 USA

[2] Oregon Hlth Sci Univ, Vollum Inst, Portland, OR 97201 USA

来源：

NATURE | 2001年 / 413卷 / 6852期

关键词：

D O I：

10.1038/35093011

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mechanotransduction-a cell's conversion of a mechanical stimulus into an electrical signal-reveals vital features of an organism's environment. From hair cells and skin mechanoreceptors in vertebrates, to bristle receptors in flies and touch receptors in worms, mechanically sensitive cells are essential in the life of an organism. The scarcity of these cells and the uniqueness of their transduction mechanisms have conspired to slow molecular characterization of the ensembles that carry out mechanotransduction. But recent progress in both invertebrates and vertebrates is beginning to reveal the identities of proteins essential for transduction.

引用

页码：194 / 202

页数：9

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