Microbiota and mucosal immunity in amphibians

被引：110

作者：

Colombo, Bruno M. ^{[1
]}

Scalvenzi, Thibault ^{[1
]}

Benlamara, Sarah ^{[1
]}

Pollet, Nicolas ^{[2
,3
]}

机构：

[1] Univ Evry Val Essonne, Inst Syst & Synthet Biol, Evry, France

[2] CNRS, Inst Syst & Synthet Biol, Evry, France

[3] Univ Paris 11, IRD, CNRS, Evolut Genome Comportement & Ecol, Gif Sur Yvette, France

来源：

FRONTIERS IN IMMUNOLOGY | 2015年 / 6卷

关键词：

small-animal model; Xenopus; microbiome; mucosal immunity; chytrid; INVARIANT T-CELLS; INNATE LYMPHOID-CELLS; SMALL INTESTINAL EPITHELIUM; TADPOLES RANA-CATESBEIANA; XENOPUS-LAEVIS TADPOLES; AFRICAN CLAWED FROG; GUT MICROBIOTA; ANTIMICROBIAL PEPTIDE; BULLFROG TADPOLES; ADULT XENOPUS;

D O I：

10.3389/fimmu.2015.00111

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We know that animals live in a world dominated by bacteria. In the last 20 years, we have learned that microbes are essential regulators of mucosal immunity. Bacteria, archeas, and viruses influence different aspects of mucosal development and function. Yet, the literature mainly covers findings obtained in mammals. In this review, we focus on two major themes that emerge from the comparative analysis of mammals and amphibians. These themes concern: (i) the structure and functions of lymphoid organs and immune cells in amphibians, with a focus on the gut mucosal immune system; and (ii) the characteristics of the amphibian microbiota and its influence on mucosal immunity. Lastly, we propose to use Xenopus tadpoles as an alternative small-animal model to improve the fundamental knowledge on immunological functions of gut microbiota.

引用

页数：15

共 139 条

[1] How vitamin A metabolizing dendritic cells are generated in the gut mucosa [J].

Agace, William W. ;

Persson, Emma K. .

TRENDS IN IMMUNOLOGY, 2012, 33 (01) :42-48

[2] Lymphoid neogenesis in chronic inflammatory diseases [J].

Aloisi, F ;

Pujol-Borrell, R .

NATURE REVIEWS IMMUNOLOGY, 2006, 6 (03) :205-217

[3] What do tadpoles really eat? Assessing the trophic status of an understudied and imperiled group of consumers in freshwater habitats [J].

Altig, Ronald ;

Whiles, Matt R. ;

Taylor, Cindy L. .

FRESHWATER BIOLOGY, 2007, 52 (02) :386-395

[4] GUT-ASSOCIATED LYMPHOID-TISSUE (GALT) IN THE AMPHIBIAN URODELE PLEURODELES-WALTL [J].

ARDAVIN, CF ;

ZAPATA, A ;

VILLENA, A ;

SOLAS, MT .

JOURNAL OF MORPHOLOGY, 1982, 173 (01) :35-41

[5] INDIGENOUS MICROBIAL FLORA AND LARGE INTESTINE IN TADPOLES [J].

BATTAGLI.P ;

BONI, P .

EXPERIENTIA, 1967, 23 (11) :950-&

[6] Towards a Better Understanding of the Use of Probiotics for Preventing Chytridiomycosis in Panamanian Golden Frogs [J].

Becker, Matthew H. ;

Harris, Reid N. ;

Minbiole, Kevin P. C. ;

Schwantes, Christian R. ;

Rollins-Smith, Louise A. ;

Reinert, Laura K. ;

Brucker, Robert M. ;

Domangue, Rickie J. ;

Gratwicke, Brian .

ECOHEALTH, 2011, 8 (04) :501-506

[7]

BEFUS AD, 1980, J IMMUNOL, V125, P2626

[8] Probiotics: Properties, Examples, and Specific Applications [J].

Behnsen, Judith ;

Deriu, Elisa ;

Sassone-Corsi, Martina ;

Raffatellu, Manuela .

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, 2013, 3 (03)

[9] Chytridiomycosis causes amphibian mortality associated with population declines in the rain forests of Australia and Central America [J].

Berger, L ;

Speare, R ;

Daszak, P ;

Green, DE ;

Cunningham, AA ;

Goggin, CL ;

Slocombe, R ;

Ragan, MA ;

Hyatt, AD ;

McDonald, KR ;

Hines, HB ;

Lips, KR ;

Marantelli, G ;

Parkes, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (15) :9031-9036

[10] Mitigating amphibian chytridiomycosis with bioaugmentation: characteristics of effective probiotics and strategies for their selection and use [J].

Bletz, Molly C. ;

Loudon, Andrew H. ;

Becker, Matthew H. ;

Bell, Sara C. ;

Woodhams, Douglas C. ;

Minbiole, Kevin P. C. ;

Harris, Reid N. .

ECOLOGY LETTERS, 2013, 16 (06) :807-820

← 1 2 3 4 5 6 7 8 9 10 →