Intramolecular trapping of esters and amides by 1-lithio-1-bromocyclopropanes

被引：6

作者：

Baird, MS ^{[1
]}

Huber, FAM

Tverezovzky, VV

Bolesov, IG

机构：

[1] Univ Coll N Wales, Dept Chem, Bangor LL57 2UW, Gwynedd, Wales

[2] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119899, Russia

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(98)01999-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 2-acyloxymethyl or 2-acylaminomethyl-1, 1-dibromocycloprapanes with methyllithium at -90 degrees C leads to selective bromine-lithium exchange and intramolecular cyclisation to give a 1-bromo-3-oxa- or 1-broma-3-oxa-bicyclo[3. 1.0]hexan-2-ol. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：9081 / 9084

页数：4

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