Lanthanide complexes with C2 symmetric ligands for use in enantioselective organic synthesis

被引：18

作者：

Aspinall, HC ^{[1
]}

Dwyer, JLM ^{[1
]}

Greeves, N ^{[1
]}

Smith, PM ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Donnan & Robert Robinson Labs, Liverpool L69 7ZD, Merseyside, England

来源：

JOURNAL OF ALLOYS AND COMPOUNDS | 2000年 / 303卷

基金：

英国工程与自然科学研究理事会;

关键词：

lanthanide; catalysis; enantioselective; pybox; binaphthol;

D O I：

10.1016/S0925-8388(00)00661-7

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

C-2 symmetric chelating ligands can be used to prepare homochiral lanthanide complexes which act as enantioselective reagents and catalysts for synthetically important reactions. [LnCl(3)(pybox)(2)] (pybox is 2,6-bis(substituted-2-oxazolin-2-yl)pyridine) catalyse the enantioselective silylcyanation of aldehydes. [Li(3)Ln(binol)(3)] (H(2)binol is binaphthol) are reagents for the enantioselective addition of MeLi to aldehydes. [La(OTf)(3)(Pr-i-pybox)(2)] and [Li(THF)(2)](2)[Li(Et2O)][Yb(R-binol)(3)] have been characterised by single crystal X-ray diffraction. (C) 2000 Elsevier Science S.A. All rights reserved.

引用

页码：173 / 177

页数：5

共 17 条

[1] A FACILE SYNTHESIS OF OPTICALLY-ACTIVE GAMMA-CYANOALLYLIC ALCOHOLS USING ASYMMETRIC HYDROCYANATION OF ALPHA,BETA-ALKENYL ALDEHYDES FOLLOWED BY STEREOSPECIFIC [3.3]SIGMATROPIC CHIRALITY TRANSFER OF THE CYANOHYDRIN ACETATES [J].