Contact investigation for tuberculosis in Taiwan contacts aged under 20 years in 2005

被引：0

作者：

Ling, D-L. ^{[1
,2
,3
]}

Liaw, Y-P. ^{[2
,3
,4
]}

Lee, C-Y. ^{[1
,5
]}

Lo, H-Y. ^{[1
,6
]}

Yang, H-L. ^{[1
]}

Chan, P-C. ^{[1
,7
]}

机构：

[1] Ctr Dis Control, Dept Hlth, Taipei 10050, Taiwan

[2] Chung Shan Med Univ, Dept Publ Hlth, Taichung, Taiwan

[3] Chung Shan Med Univ, Inst Publ Hlth, Taichung, Taiwan

[4] Chung Shan Med Univ Hosp, Dept Family & Community Med, Taichung, Taiwan

[5] Natl Taiwan Univ, Coll Publ Hlth, Inst Hlth Policy & Management, Taipei 10764, Taiwan

[6] Natl Yang Ming Univ, Community Med Res Ctr, Inst Publ Hlth, Taipei 112, Taiwan

[7] Natl Taiwan Univ, Coll Publ Hlth, Inst Epidemiol & Prevent Med, Taipei 10764, Taiwan

来源：

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | 2011年 / 15卷 / 01期

关键词：

contact investigation; latent TB infection; active case finding; infant and children; tuberculosis; LATENT TUBERCULOSIS; CLOSE CONTACTS; INFECTION; DETECT;

D O I：

暂无

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

OBJECTIVE: To measure the tuberculosis (TB) incidence rate and assess the relative risk of TB disease in contacts based on the tuberculin skin test (TST) and sputum status of index cases. DESIGN: All contacts aged < 20 years who were exposed to a TB case in 2005 were cross-matched using an electronic surveillance system to estimate TB incidence over a 24-month follow-up period. RESULTS: Among 6959 contacts there were 67 secondary cases (1%). The incidence was highest in the first year after exposure and decreased by half in the second year (P = 0.001). The relative risks of developing TB in contacts aged 0-4, 5-9, 10-14 and 15-19 years were respectively 325, 209, 337 and 53 times greater than for the general population. The hazard ratio of developing TB among contacts with a TST >= 15 mm induration was 12 times higher than for those with a TST < 5 mm (P = 0.003). CONCLUSIONS: The relative risk of developing TB disease within 24 months of exposure was approximately 200-300 times greater for contacts aged < 15 years. The majority developed TB within 12 months of exposure.

引用

页码：50 / 55

页数：6

共 20 条

[1] [Anonymous], 2006, STOP TB STRAT BUILD
[2] [Anonymous], 2006, WHOHTMTB2006371
[3] Bureau of National Health Insurance Taiwan, 2010, STAT ANN REP INS COV
[4] [Centers for Disease Control Department of Health Taiwan], 2002, MAN TUB CONTR
[5] [Centers for Disease Control Department of Health Taiwan], 2001, STRAT TUB CONTR TUB
[6] [Centers for Disease Control Department of Health Taiwan], 2006, TAIW GUID TB DIAGN T
[7] [Centers for Disease Control Department of Health Taiwan], 2006, STAT COMM DIS SURV R
[8] [Centers for Disease Control Department of Health Taiwan], 2009, TAIW TUB CONTR REP 2
[9] Chan PC, 2008, INT J TUBERC LUNG D, V12, P1401
[10] Chee CBE, 2004, INT J TUBERC LUNG D, V8, P226

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