Breakthroughs in the Health Effects of Plant Food Bioactives: A Perspective on Microbiomics, Nutri(epi)genomics, and Metabolomics

被引：30

作者：

Bayram, Banu ^{[1
]}

Gonzalez-Sarrias, Antonio ^{[2
]}

Istas, Geoffrey ^{[3
]}

Garcia-Aloy, Mar ^{[4
,5
]}

Morand, Christine ^{[6
]}

Tuohy, Kieran ^{[7
]}

Garcia-Villalba, Rocio ^{[2
]}

Mena, Pedro ^{[8
]}

机构：

[1] Univ Hlth Sci, Dept Nutr & Dietet, Tibbiye Cad 38, TR-34668 Istanbul, Turkey

[2] CSIC, CEBAS, Lab Food & Hlth, Res Grp Qual Safety & Bioact Plant Foods, Campus Espinardo, E-30100 Murcia, Spain

[3] Kings Coll London, Fac Life Sci & Med, Dept Nutr Sci, London WC2R 2LS, England

[4] Univ Barcelona, Fac Pharm & Food Sci, Dept Nutr Food Sci & Gastron, Biomarkers & Nutrimetabol Lab,XaRTA,INSA, E-08007 Barcelona, Spain

[5] Inst Salud Carlos III, CIBER Fragilidad & Envejecimiento Saludable CIBER, Barcelona 28029, Spain

[6] Univ Clermont Auvergne, INRA, UNH, CRNH Auvergne, F-63000 Clermont Ferrand, France

[7] Fdn Edmund Mach, Res & Innovat Ctr, Dept Food Qual & Nutr, Via E Mach 1, I-38010 Trento, Italy

[8] Univ Parma, Dept Food & Drugs, Human Nutr Unit, Med Sch Bldg C,Via Volturno 39, I-43125 Parma, Italy

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2018年 / 66卷 / 41期

关键词：

phytochemicals; interindividual variability; personalized nutrition; metabolome; gut microbiota; BIOMARKERS; CONSUMPTION; TOOL;

D O I：

10.1021/acs.jafc.8b03385

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

Plant bioactive compounds consumed as part of our diet are able to influence human health. They include secondary metabolites like (poly)phenols, carotenoids, glucosinolates, alkaloids, and terpenes. Although much knowledge has been gained, there is still need for studies unravelling the effects of plant bioactives on cardiometabolic health at the individual level, using cutting-edge high-resolution and data-rich holistic approaches. The aim of this Perspective is to review the prospects of microbiomics, nutrigenomics and nutriepigenomics, and metabolomics to assess the response to plant bioactive consumption while considering interindividual variability. Insights for future research in the field toward personalized nutrition are discussed.

引用

页码：10686 / 10692

页数：7

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