Incorporation of single-wall carbon nanotubes into an organic polymer monolithic stationary phase for μ-HPLC and capillary electrochromatography

被引：183
作者：
Li, Y [1 ]
Chen, Y [1 ]
Xiang, R [1 ]
Ciuparu, D [1 ]
Pfefferle, LD [1 ]
Horwáth, C [1 ]
Wilkins, JA [1 ]
机构：
[1] Yale Univ, Dept Chem Engn, New Haven, CT 06520 USA
来源：
ANALYTICAL CHEMISTRY | 2005年 / 77卷 / 05期
关键词：
D O I：
10.1021/ac048299h
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Single-wall carbon nanotubes (SWNT) were incorporated into an organic polymer monolith containing vinylbenzyl chloride (VBC)and ethylene dimethacrylate (EDMA) to form a novel monolithic stationary phase for high-performance liquid chromatography (HPLC) and capillary electrochromatography (CEC). The retention behavior of neutral compounds on this poly(VBC-EDMA-SWNT) monolith was examined by separating a mixture of small organic molecules using micro-HPLC. The result indicated that incorporation of SANT enhanced chromatographic retention of small neutral molecules in reversed-phase HPLC presumably because of their strongly hydrophobic characteristics. The stationary phase was formed inside a fused-silica capillary whose lumen was coated with covalently bound polyethyleneimine (PEI). The annular electroosmotic flow (EOF) generated by the PEI coating allowed peptide separation by CEC in the counterdirectional mode. Comparison of peptide separations on poly(VBC-EDMA-SWNT) and on poly(VBC-EDMA) with annular EOF generation revealed that the incorporation of SWNT into the monolithic stationary phase improved peak efficiency and influenced chromatographic retention. The structures of pretreated SWNT and poly(VBC-EDMA-SWNT) monolith were examined by high-resolution transmission electron microscopy, Raman spectroscopy, scanning electron microscopy, and multipoint BET nitrogen adsorption/desorption.
引用
收藏
页码：1398 / 1406
页数：9
相关论文
共 43 条
[1]   Location-specific biological functionalization on nanotubes: Attachment of proteins at the ends of nanotubes using Au nanocrystal masks [J].
Banerjee, IA ;
Yu, LT ;
Matsui, H .
NANO LETTERS, 2003, 3 (03) :283-287
[2]   Static and dynamic wetting measurements of single carbon nanotubes [J].
Barber, AH ;
Cohen, SR ;
Wagner, HD .
PHYSICAL REVIEW LETTERS, 2004, 92 (18) :186103-1
[3]   Length separation of Zwitterion-functionalized single wall carbon nanotubes by GPC [J].
Chattopadhyay, D ;
Lastella, S ;
Kim, S ;
Papadimitrakopoulos, F .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (05) :728-729
[4]   Dissolution of full-length single-walled carbon nanotubes [J].
Chen, J ;
Rao, AM ;
Lyuksyutov, S ;
Itkis, ME ;
Hamon, MA ;
Hu, H ;
Cohn, RW ;
Eklund, PC ;
Colbert, DT ;
Smalley, RE ;
Haddon, RC .
JOURNAL OF PHYSICAL CHEMISTRY B, 2001, 105 (13) :2525-2528
[5]   Solution properties of single-walled carbon nanotubes [J].
Chen, J ;
Hamon, MA ;
Hu, H ;
Chen, YS ;
Rao, AM ;
Eklund, PC ;
Haddon, RC .
SCIENCE, 1998, 282 (5386) :95-98
[6]   Synthesis of uniform diameter single wall carbon nanotubes in Co-MCM-41: effects of CO pressure and reaction time [J].
Chen, Y ;
Ciuparu, D ;
Lim, S ;
Yang, YH ;
Haller, GL ;
Pfefferle, L .
JOURNAL OF CATALYSIS, 2004, 226 (02) :351-362
[7]   Synthesis of uniform diameter single-wall carbon nanotubes in Co-MCM-41: effects of the catalyst prereduction and nanotube growth temperatures [J].
Chen, Y ;
Ciuparu, D ;
Lim, SY ;
Yang, YH ;
Haller, GL ;
Pfefferle, L .
JOURNAL OF CATALYSIS, 2004, 225 (02) :453-465
[8]   Uniform-diameter single-walled carbon nanotubes catalytically grown in cobalt-incorporated MCM-41 [J].
Ciuparu, D ;
Chen, Y ;
Lim, S ;
Haller, GL ;
Pfefferle, L .
JOURNAL OF PHYSICAL CHEMISTRY B, 2004, 108 (02) :503-507
[9]   Carbon nanotubes: opportunities and challenges [J].
Dai, HJ .
SURFACE SCIENCE, 2002, 500 (1-3) :218-241
[10]   Chromatographic size separation of single-wall carbon nanotubes [J].
Duesberg, GS ;
Muster, J ;
Krstic, V ;
Burghard, M ;
Roth, S .
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING, 1998, 67 (01) :117-119
12345