Donor-derived tuberculosis (TB): isoniazid-resistant TB transmitted from a lung transplant donor with inadequately treated latent infection

被引：11

作者：

Jensen, T. O. ^{[1
,2
]}

Darley, D. R. ^{[3
]}

Goeman, E. E. ^{[4
]}

Shaw, K. ^{[5
,6
]}

Marriott, D. J. ^{[1
,4
]}

Glanville, A. R. ^{[2
]}

机构：

[1] St Vincents Hosp, Dept Infect Dis, Sydney, NSW, Australia

[2] Univ New South Wales, Sch Med Sci, Sydney, NSW, Australia

[3] St Vincents Hosp, Lung Transplant Unit, Sydney, NSW, Australia

[4] St Vincents Hosp, Dept Microbiol, Sydpath, Sydney, NSW, Australia

[5] South Eastern Sydney Local Hlth Dist, TB Program, Sydney, NSW, Australia

[6] St Vincents Hosp, Sydney, NSW, Australia

来源：

TRANSPLANT INFECTIOUS DISEASE | 2016年 / 18卷 / 05期

关键词：

lung transplantation; tuberculosis; latent infection; isoniazid resistance;

D O I：

10.1111/tid.12580

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Donor-derived tuberculosis (TB) is an increasingly recognized complication of solid organ transplantation. We report a case of isoniazid-resistant pulmonary TB in a lung transplant recipient. The patient acquired the infection from the lung donor who was previously empirically treated with isoniazid for latent TB. The case highlights the caveat that, while adequate treatment of latent TB with isoniazid is presumed, meticulous screening of donors is required.

引用

页码：782 / 784

页数：3

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